Schwarz Lauren R, Thurstin Adrian H, Levine Lindsay A
Department of Psychiatry, University of Alabama at Birmingham, Birmingham, Alabama 63144, USA.
Appl Neuropsychol. 2010 Jan;17(1):73-7. doi: 10.1080/09084280903519831.
Moyamoya disease (MMD) is a rare cerebral vasculopathy with limited information on the associated cognitive and emotional sequelae, particularly presenting in a psychiatric setting. We present the case of a 25-year-old female with a history of MMD and depressive disorder. She underwent revascularization surgery following an ischemic stroke at age 15 years. Magnetic resonance imaging at the time of the current assessment revealed markedly abnormal appearance in the anterior cerebral circulation with extensive periventricular collateral vasculature involvement. Neuropsychological assessment data revealed deficits in inhibition and problem-solving, consistent with frontal lobe dysfunction. We discuss the importance of further research on the neuropsychological sequelae of MMD.
烟雾病（MMD）是一种罕见的脑血管病，关于其相关认知和情感后遗症的信息有限，尤其在精神科环境中表现出来。我们报告一例有烟雾病和抑郁症病史的25岁女性病例。她在15岁时因缺血性中风接受了血管重建手术。当前评估时的磁共振成像显示大脑前循环明显异常，伴有广泛的脑室周围侧支血管受累。神经心理学评估数据显示存在抑制和解决问题方面的缺陷，与额叶功能障碍一致。我们讨论了进一步研究烟雾病神经心理学后遗症的重要性。
