Khalepo O V, Molotkov O V, Eshkina S L
Patol Fiziol Eksp Ter. 2009 Oct-Dec(4):11-5.
Laser Doppler flowmetry was used to study the indicators characterizing the peripheral blood circulation in the skin, regulatory mechanisms, and the compensatory capacities of the microcirculatory bed in 32 patients aged 45-60 years in the course of primary transmural myocardial infarction during exercise tests. Significant disturbances of the mechanism responsible for regulating the peripheral blood circulation system and chiefly its active components were detected in the presence of adequate blood filling of microvessels. There was a drastic decrease in the reserves of skin microvascular endothelial activity during ionophoresis of sodium nitroprusside and acetylcholine, the maximum degree of disturbances being observed on day 10 of myocardial infarction development.
采用激光多普勒血流仪，对32例45 - 60岁原发性透壁性心肌梗死患者在运动试验过程中，表征皮肤外周血液循环的指标、调节机制以及微循环床的代偿能力进行了研究。在微血管血液充盈充足的情况下，检测到负责调节外周血液循环系统及其主要活性成分的机制存在显著紊乱。在硝普钠和乙酰胆碱离子导入过程中，皮肤微血管内皮活性储备急剧下降，在心肌梗死发生第10天观察到最大程度的紊乱。
