Abramenko I V, Evsev'eva A I, Gluzman D F, Pisniachevskaia G V, Poludnenko L Iu
Vopr Onkol. 1991;37(1):40-4.
Pleural cavity exudates obtained from 26 patients with cancer of the lung, ovary, stomach and breast and 13 cases of nononcological pathologies were studied using enzymatic cytochemical methods and monoclonal antibodies. A complex of tissue markers (carcinoembryonic antigen, 90 kdalton glycoproteid, activity of alkaline phosphatase and nonspecific alpha-naphthylacetate esterase, and PAS-positive bodies) was identified. It allows to differentiate between malignant and mesothelial cells in smears prepared from exudates.
采用酶细胞化学方法和单克隆抗体,对26例肺癌、卵巢癌、胃癌和乳腺癌患者以及13例非肿瘤性病变患者的胸腔积液进行了研究。鉴定出一组组织标志物(癌胚抗原、90千道尔顿糖蛋白、碱性磷酸酶和非特异性α-萘乙酸酯酶活性以及PAS阳性小体)。这有助于在由渗出液制备的涂片上区分恶性细胞和间皮细胞。