Department of Health Evidence and Policy, Mount Sinai School of Medicine, New York, NY 10029, USA.
Am J Public Health. 2010 Apr 1;100 Suppl 1(Suppl 1):S232-9. doi: 10.2105/AJPH.2009.170910. Epub 2010 Feb 10.
Our community-academic partnership employed community-based participatory research to develop and pilot a simple, peer-led intervention to promote weight loss, which can prevent diabetes and eliminate racial/ethnic disparities in incident diabetes among overweight adults with prediabetes.
We recruited overweight adults at community sites, performed oral glucose tolerance testing to identify persons with blood glucose levels in the prediabetes range, and randomized eligible people to a peer-led lifestyle intervention group or delayed intervention in 1 year. Outcomes, including weight, blood pressure, and health behaviors, were measured at baseline and 3, 6, and 12 months.
More than half of those tested (56%, or 99 of 178) had prediabetes and enrolled in the study. Participants were predominantly Spanish-speaking, low-income, undereducated women. The intervention group lost significantly more weight than the control group and maintained weight loss at 12 months (7.2 versus 2.4 pounds; P < .01). One fourth (24 of 99) of participants progressed to diabetes.
In underserved minority communities, prediabetes prevalence may be higher than previously reported. Low-cost, community-based interventions can succeed in encouraging weight loss to prevent diabetes.
我们的社区学术合作采用社区参与式研究，开发并试行一种简单的、以同伴为基础的干预措施，以促进超重的、患有前驱糖尿病的成年人减肥，从而预防糖尿病，并消除糖尿病发病方面的种族/民族差异。
我们在社区场所招募超重成年人，通过口服葡萄糖耐量试验来确定血糖处于前驱糖尿病范围的人，并将符合条件的人随机分为同伴主导的生活方式干预组或 1 年后的延迟干预组。在基线和 3、6、12 个月时测量体重、血压和健康行为等结果。
超过一半的受检者（56%，或 178 人中有 99 人）患有前驱糖尿病并参加了这项研究。参与者主要是讲西班牙语、低收入、受教育程度低的女性。干预组比对照组体重减轻更多，并且在 12 个月时保持体重减轻（7.2 磅对 2.4 磅；P <.01）。四分之一（99 人中有 24 人）的参与者进展为糖尿病。
在服务不足的少数族裔社区中，前驱糖尿病的患病率可能高于先前报告的水平。低成本的社区为基础的干预措施可以成功地鼓励减肥以预防糖尿病。
