氟西汀治疗引起的锥体外系副作用和自杀意念：病例报告。
Extrapyramidal side effects and suicidal ideation under fluoxetine treatment: a case report.
机构信息
Second Department of Psychiatry, Athens University Medical School, 'Attikon' General Hospital, Athens, Greece.
出版信息
Ann Gen Psychiatry. 2010 Jan 18;9:5. doi: 10.1186/1744-859X-9-5.
Abstract
BACKGROUND
We present the case of a 52-year-old woman with depression who developed extrapyramidal symptoms (mainly parkinsonism) and suicidal ideation while on fluoxetine.
METHODS
The patient underwent neurological and neuroimaging examination.
RESULTS
The patient's neurological and neuroimaging examinations were normal and there was no other cause of extrapyramidal symptoms. The patient showed remission of the aforementioned symptomatology when fluoxetine was discontinued.
CONCLUSIONS
This case shows that fluoxetine can be associated with extrapyramidal symptoms, and this may have an aggravating affect on clinical depression progress and the emergence of suicidal ideation.
摘要
背景
我们报告了一例 52 岁女性抑郁症患者，在服用氟西汀时出现锥体外系症状（主要为帕金森病）和自杀意念。
方法
患者接受了神经学和神经影像学检查。
结果
患者的神经学和神经影像学检查均正常，且不存在其他锥体外系症状的病因。停用氟西汀后，患者上述症状缓解。
结论
本病例表明氟西汀可能与锥体外系症状相关，这可能加重临床抑郁症的进展并导致自杀意念的出现。
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