ADOS 修订算法的诊断有效性提高：独立样本的复制研究。
Improved diagnostic validity of the ADOS revised algorithms: a replication study in an independent sample.
机构信息
Karakter Child and Adolescent Psychiatry University Center, Reinier Postlaan 12, 6525 GC Nijmegen, The Netherlands.
出版信息
J Autism Dev Disord. 2010 Jun;40(6):689-703. doi: 10.1007/s10803-009-0915-0.
Abstract
Recently, Gotham et al. (2007) proposed revised algorithms for the Autism Diagnostic Observation Schedule (ADOS) with improved diagnostic validity. The aim of the current study was to replicate predictive validity, factor structure, and correlations with age and verbal and nonverbal IQ of the ADOS revised algorithms for Modules 1 and 2 in a large independent Dutch sample (N = 532). Results showed that the improvement of diagnostic validity was most apparent for autism, except in very young or low functioning children. Results for other autism spectrum disorders were less consistent. Overall, these findings support the use of the more homogeneous revised algorithms, with the use of similar items across developmental cells making it easier to compare ADOS scores within and between individuals.
摘要
最近，Gotham 等人（2007 年）提出了修订后的孤独症诊断观察量表（ADOS）算法，以提高诊断的有效性。本研究的目的是在一个大型的独立荷兰样本（N=532）中复制 ADOS 修订算法在模块 1 和 2 的预测有效性、因子结构以及与年龄、语言和非语言智商的相关性。结果表明，诊断有效性的提高在孤独症方面最为明显，除了非常年幼或功能低下的儿童。其他孤独症谱系障碍的结果则不太一致。总的来说，这些发现支持使用更同质的修订算法，使用跨发育单元的相似项目，使得更容易在个体内部和之间比较 ADOS 分数。
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