Cattedra di Reumatologia, Università di Pisa, Pisa, Italy.
Clin Exp Rheumatol. 2009 Nov-Dec;27(6):897-901.
Systemic lupus erhthematosus (SLE) is an autoimmune multisystem disorder characterised by frequent musculoskeletal manifestations. Joint involvement in SLE is usually not erosive or destructive but some patients develop hand erosive arthritis or deforming arthropathy of the hand (respectively "rhupus" hand and Jaccoud arthritis). To date, few studies, evaluated joint and tendon involvement in SLE patients by US. We studied wrist and hand structure, using ultrasound, in 50 patients affected by SLE, detecting inflammatory joint involvement in 80% of them at the wrist and in 50% at the hand. Tenosynovitis was visualised in 14 patients, while structural damage was present in 12% of the SLE group. Those results reinforce the importance of including musculoskeletal ultrasound in the patient assessment, especially in those cases in which physical examination is not conclusive.
系统性红斑狼疮（SLE）是一种自身免疫性多系统疾病，其特征是频繁出现肌肉骨骼表现。SLE 患者的关节受累通常不会发生侵蚀或破坏，但有些患者会发展为手部侵蚀性关节炎或畸形性手关节炎（分别为“rhupus”手和杰科德关节炎）。迄今为止，很少有研究通过 US 评估 SLE 患者的关节和肌腱受累情况。我们使用超声检查了 50 例 SLE 患者的手腕和手部结构，在其中 80%的患者手腕和 50%的患者手部发现了炎症性关节受累。14 例患者出现腱鞘炎，而 SLE 组中有 12%的患者出现结构损伤。这些结果强调了在患者评估中包括肌肉骨骼超声的重要性，尤其是在体格检查不明确的情况下。
