痛风性指关节炎的危险因素。

Risk factors for gouty dactylitis.

机构信息

Clinica Reumatologica, Dipartimento di Medicina Interna, Università di Genova, Italy.

出版信息

Clin Exp Rheumatol. 2009 Nov-Dec;27(6):993-5.

PMID:20149319

Abstract

OBJECTIVE

To investigate the risk factors associated with dactylitis in gout.

METHODS

The questionnaires of 73 consecutive gouty patients, diagnosed according to the ACR criteria, were reviewed. They were consecutively screened for the presence of dactylitis.

RESULTS

Seven out of 73 (9.6%) patients showed dactylitis. They had (1) longer disease duration, (2) a higher number of involved joints, (3) higher serum uric acid concentration, (4) more tophi, (5) higher ESR, and (6) a higher number of ACR criteria besides crystal identification, than the others. By logistic regression, renal stones (OR 13.3, 95% CI 1.1-158.3), upper extremity involvement (OR 4.9, 95% CI 1.4-16.6), number of ACR criteria (OR 1.9, 95% CI 1.1-3.3), and ESR (OR 1.02, 95% CI 1-1.04), significantly predicted dactylitis.

CONCLUSIONS

Dactylitis is a feature of gout representing an indicator of disease severity.

摘要

目的

探讨与痛风性关节炎患者跖趾炎相关的危险因素。

方法

对 73 例连续痛风患者（符合 ACR 标准）的问卷调查表进行回顾性分析。连续筛查这些患者是否存在跖趾炎。

结果

73 例患者中 7 例（9.6%）患有跖趾炎。与无跖趾炎患者相比，这些患者具有以下特征：（1）疾病持续时间更长；（2）累及关节更多；（3）血清尿酸浓度更高；（4）存在更多痛风石；（5）ESR 更高；（6）除晶体鉴定外，还符合更多的 ACR 标准。通过逻辑回归分析，肾结石（OR 13.3，95%CI 1.1-158.3）、上肢受累（OR 4.9，95%CI 1.4-16.6）、ACR 标准数量（OR 1.9，95%CI 1.1-3.3）和 ESR（OR 1.02，95%CI 1-1.04）显著预测了跖趾炎。