Rheumatology Department, Henri Mondor Hospital, Paris XII University, Créteil, France.
Clin Exp Rheumatol. 2009 Nov-Dec;27(6):999-1000.
Concern has arisen regarding a possible increase in the risk of malignant diseases such as lymphoproliferative disorders in a patient taking TNF-alpha antagonists for the treatment of chronic inflammatory diseases. The evidence of a causal link remains unclear. We report a case of 60-year-old male patient who developed acute myeloid leukemia during infliximab therapy for ankylo-sing spondylitis.
人们对接受 TNF-α 拮抗剂治疗慢性炎症性疾病的患者恶性疾病（如淋巴增生性疾病）风险增加表示担忧。因果关系的证据仍不清楚。我们报告了一例 60 岁男性患者，在接受英夫利昔单抗治疗强直性脊柱炎期间发生急性髓系白血病。
