Center for Reproductive Medicine, Universitair Ziekenhuis Brussel, Brussels, Belgium.
Fertil Steril. 2010 Oct;94(5):1922-4. doi: 10.1016/j.fertnstert.2009.12.070. Epub 2010 Feb 10.
Fifty healthy women, aged 18-39 years with no known risk of ovarian hyperstimulation were treated with 100 or 150 μg corifollitropin alfa (dependent on body weight) in a long GnRH agonist protocol. At these doses, corifollitropin alfa initiated and supported growth of a large cohort of follicles during the first week of ovarian stimulation.
50 名 18-39 岁的健康女性,无卵巢过度刺激综合征的已知风险,根据体重接受 100 或 150μg 戈那瑞林的长 GnRH 激动剂方案治疗。在这些剂量下,戈那瑞林在卵巢刺激的第一周启动并支持了大量卵泡的生长。