Instituto Oswaldo Cruz, FIOCRUZ, Av. Brasil, 4365, Rio de Janeiro, RJ 21040-360, Brazil.
Res Vet Sci. 2010 Aug;89(1):27-35. doi: 10.1016/j.rvsc.2010.01.001. Epub 2010 Feb 11.
A 4-year longitudinal epidemiological study was carried out to evaluate the effect of infection by Trypanosoma cruzi and three intestinal helminth species on the health of golden and golden-headed lion tamarins. We evaluated health using analysis of blood counts, serum proteins, electrophoretograms, electrocardiograms and a health ranking based on physiological parameters. Among the helminths, Trichostrongylidae was demonstrated as the most pathogenic, followed by Prosthenorchis sp.; concomitant infection by Spiruridae may exacerbate the negative effects of the other two helminths. T. cruzi infection was not highly detrimental to the health of the study animals and was correlated with increased resilience to helminths. Tamarins younger than 1-year of age or older than 4-years had lower health condition. Golden-headed lion tamarins were in lower health condition because of higher parasitic prevalence. Our data suggest that when parasite community pathogenicity and prevalence are high, natural selection will allow survival only of lion tamarins in the best health condition.
进行了一项为期 4 年的纵向流行病学研究，以评估感染克氏锥虫和三种肠道寄生虫对金狮面狨和金头狮面狨健康的影响。我们通过血液计数分析、血清蛋白电泳、心电图和基于生理参数的健康评分来评估健康状况。在这些寄生虫中，旋毛线虫被证明是最具致病性的，其次是 Prosthenorchis sp.；旋尾线虫的合并感染可能会加剧其他两种寄生虫的负面影响。克氏锥虫感染对研究动物的健康没有很大的危害，并且与对寄生虫的抵抗力增强有关。年龄小于 1 岁或大于 4 岁的狨猴健康状况较差。金头狮面狨的健康状况较差是因为寄生虫的流行率较高。我们的数据表明，当寄生虫群落的致病性和流行率较高时，自然选择只会让健康状况最好的狮面狨生存下来。
