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圈养狮狨（狮狨属）群体中克氏锥虫TcII和TcI感染情况：一项为期11年的随访研究

Infection with Trypanosoma cruzi TcII and TcI in free-ranging population of lion tamarins (Leontopithecus spp): an 11-year follow-up.

作者信息

Lisboa Cristiane Varella, Monteiro Rafael Veríssimo, Martins Andreia Fonseca, Xavier Samantha Cristina das Chagas, Lima Valdirene Dos Santos, Jansen Ana Maria

机构信息

Laboratório de Biologia de Tripanosomatídeos, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, RJ, Brasil.

出版信息

Mem Inst Oswaldo Cruz. 2015 May;110(3):394-402. doi: 10.1590/0074-02760140400. Epub 2015 Apr 28.

DOI:10.1590/0074-02760140400
PMID:25946156
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4489477/
Abstract

Here, we present a review of the dataset resulting from the 11-years follow-up of Trypanosoma cruzi infection in free-ranging populations of Leontopithecus rosalia (golden lion tamarin) and Leontopithecus chrysomelas (golden-headed lion tamarin) from distinct forest fragments in Atlantic Coastal Rainforest. Additionally, we present new data regarding T. cruzi infection of small mammals (rodents and marsupials) that live in the same areas as golden lion tamarins and characterisation at discrete typing unit (DTU) level of 77 of these isolates. DTU TcII was found to exclusively infect primates, while TcI infected Didelphis aurita and lion tamarins. The majority of T. cruzi isolates derived from L. rosalia were shown to be TcII (33 out 42) Nine T. cruzi isolates displayed a TcI profile. Golden-headed lion tamarins demonstrated to be excellent reservoirs of TcII, as 24 of 26 T. cruzi isolates exhibited the TcII profile. We concluded the following: (i) the transmission cycle of T. cruzi in a same host species and forest fragment is modified over time, (ii) the infectivity competence of the golden lion tamarin population fluctuates in waves that peak every other year and (iii) both golden and golden-headed lion tamarins are able to maintain long-lasting infections by TcII and TcI.

摘要

在此，我们对来自大西洋沿岸雨林不同森林片段的野生红背松鼠猴（金头狮面狨）和黄头狮面狨群体中克氏锥虫感染进行11年随访所产生的数据集进行综述。此外，我们还展示了关于与金头狮面狨生活在同一区域的小型哺乳动物（啮齿动物和有袋动物）的克氏锥虫感染的新数据，以及对其中77株分离株在离散分型单元（DTU）水平的特征描述。发现DTU TcII仅感染灵长类动物，而TcI感染南美袋鼬和狮面狨。来自红背松鼠猴的大多数克氏锥虫分离株显示为TcII（42株中有33株）。9株克氏锥虫分离株呈现TcI谱型。黄头狮面狨被证明是TcII的优秀宿主，因为26株克氏锥虫分离株中有24株呈现TcII谱型。我们得出以下结论：（i）克氏锥虫在同一宿主物种和森林片段中的传播周期随时间而改变，（ii）金头狮面狨群体的感染能力呈波浪式波动，每隔一年达到峰值，（iii）金头狮面狨和黄头狮面狨都能够维持由TcII和TcI引起的长期感染。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2f0/4489477/7c4c31543e83/0074-0276-mioc-110-3-0394-gf04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2f0/4489477/1757c4fad569/0074-0276-mioc-110-3-0394-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2f0/4489477/58aa0b2af834/0074-0276-mioc-110-3-0394-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2f0/4489477/6106e4908c71/0074-0276-mioc-110-3-0394-gf03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2f0/4489477/7c4c31543e83/0074-0276-mioc-110-3-0394-gf04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2f0/4489477/1757c4fad569/0074-0276-mioc-110-3-0394-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2f0/4489477/58aa0b2af834/0074-0276-mioc-110-3-0394-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2f0/4489477/6106e4908c71/0074-0276-mioc-110-3-0394-gf03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2f0/4489477/7c4c31543e83/0074-0276-mioc-110-3-0394-gf04.jpg

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2
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J Anim Ecol. 2014 Jan;83(1):30-40. doi: 10.1111/1365-2656.12096. Epub 2013 Jun 3.
3
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Front Parasitol. 2025 Feb 17;4:1547701. doi: 10.3389/fpara.2025.1547701. eCollection 2025.
4
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6
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7
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