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儿童社区获得性非典型艰难梭菌病发病率上升。

Increasing incidence of community-associated atypical Clostridium difficile disease in children.

作者信息

Baker Susan S, Faden Howard, Sayej Wael, Patel Raza, Baker Robert D

机构信息

University at Buffalo, The State University of New York, School of Medicine and Biomedical Sciences, and Women and Children's Hospital of Buffalo, Buffalo, NY, USA.

出版信息

Clin Pediatr (Phila). 2010 Jul;49(7):644-7. doi: 10.1177/0009922809360927. Epub 2010 Feb 11.

DOI:10.1177/0009922809360927
PMID:20150212
Abstract

Forty-one children with a variety of gastrointestinal complaints were diagnosed with Clostridium difficile infections as part of a routine screen over 3 years. The infection had not been suspected prior to the screen. Each child responded to treatment with metronidazole with resolution of their symptoms. These data suggest that community-associated C difficile is increasing and may produce atypical disease and lead to misdiagnosis.

摘要

在为期3年的常规筛查中,41名有各种胃肠道不适症状的儿童被诊断出感染艰难梭菌。在筛查之前并未怀疑有该感染。每个孩子对甲硝唑治疗均有反应,症状得到缓解。这些数据表明,社区相关性艰难梭菌感染正在增加,可能会导致非典型疾病并引起误诊。

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Increasing incidence of community-associated atypical Clostridium difficile disease in children.儿童社区获得性非典型艰难梭菌病发病率上升。
Clin Pediatr (Phila). 2010 Jul;49(7):644-7. doi: 10.1177/0009922809360927. Epub 2010 Feb 11.
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A New Lab Developed Real Time PCR Assay for Direct Detection of C. Difficle from Stool Sample without DNA Extraction.一个新实验室开发了一种无需DNA提取即可直接从粪便样本中检测艰难梭菌的实时PCR检测方法。
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