Department of Radiology, University of Michigan Health System, C. S. Mott Children's Hospital, 1500 E. Medical Center Dr., Ann Arbor, MI 48103, USA.
Pediatr Radiol. 2010 Aug;40(8):1421-5. doi: 10.1007/s00247-009-1539-4. Epub 2010 Feb 12.
Xanthogranulomatous pyelonephritis (XGP) is a chronic suppurative infectious process that only rarely affects pediatric patients, and most commonly occurs in the setting of a large obstructing calculus. Histologically, XGP is characterized by the presence of chronic inflammation and lipid-laden macrophages. This case report illustrates the radiological, surgical, and pathologic findings in a young patient who presented to our institution for treatment of this uncommon condition. Although rare, xanthogranulomatous pyelonephritis is a clinically important entity that can affect pediatric patients. This condition should be considered in the differential diagnosis for an atypical-appearing renal mass.
黄色肉芽肿性肾盂肾炎(XGP)是一种慢性化脓性感染过程,仅很少发生于儿科患者,且最常发生于大的梗阻性结石的情况下。组织学上,XGP 的特征是存在慢性炎症和含脂巨噬细胞。本病例报告说明了在一位年轻患者中出现这种罕见情况时,放射学、外科和病理学检查的结果。尽管罕见,但黄色肉芽肿性肾盂肾炎是一种具有临床重要性的实体,可以影响儿科患者。在对不典型肾肿块进行鉴别诊断时,应考虑这种情况。