Matthews G J, McLorie G A, Churchill B A, Steckler R E, Khoury A E
Hospital for Sick Children, Toronto, Ontario, Canada.
J Urol. 1995 Jun;153(6):1958-9.
We observed xanthogranulomatous pyelonephritis in 5 of 27 nephrectomies (18.5%) performed for end stage pyelonephritis. Two patients were 5 months old or younger, of normal birth weight and the products of uncomplicated full-term pregnancies. In all cases clinical histories and findings were consistent with xanthogranulomatous pyelonephritis yet this diagnosis was suspected prospectively in only 1 case. Our observations, supported by recent literature, suggest that xanthogranulomatous pyelonephritis may occur more commonly than previously reported. In addition, the clinical and pathological expression of this process in the pediatric population appears to be no different from that in adults. The true incidence and presumed chronicity of this process need to be reevaluated in light of recent data.
在因终末期肾盂肾炎而进行的27例肾切除手术中，我们观察到5例（18.5%）存在黄色肉芽肿性肾盂肾炎。两名患者年龄在5个月及以下，出生体重正常，均为足月顺产且孕期无并发症。所有病例的临床病史和检查结果均与黄色肉芽肿性肾盂肾炎相符，但仅有1例在术前被怀疑为此病。我们的观察结果，得到了近期文献的支持，提示黄色肉芽肿性肾盂肾炎的发病率可能比之前报道的更高。此外，该疾病在儿童群体中的临床和病理表现似乎与成人并无差异。鉴于近期的数据，需要对这一疾病的实际发病率及假定的慢性病程进行重新评估。
