Duke University Medical Center, Durham, North Carolina.
University of Missouri-Kansas City, Kansas City, Missouri.
J Nerv Ment Dis. 2023 Aug 1;211(8):639-640. doi: 10.1097/NMD.0000000000001633.
Intracranial lipomas are extremely rare fat-containing lesions that occur due to the abnormal differentiation of embryonic meninges. Interhemispheric lipomas that are closely related to the corpus callosum are also referred to as pericallosal lipomas and are the most common subtype. Pericallosal lipomas are associated with varying degrees of dysgenesis of the corpus callosum and therefore have a broad clinical presentation. Herein, we describe a case of a 15-year-old man who presented with a history of developmental delay and psychiatric symptoms and was incidentally found to have a pericallosal lipoma on magnetic resonance imaging, prompting clinical correlation.
颅内脂肪瘤是一种极为罕见的含脂肪病变,是由于胚胎脑膜的异常分化引起的。与胼胝体密切相关的脑室内脂肪瘤也被称为胼胝体脂肪瘤,是最常见的亚型。胼胝体脂肪瘤伴有胼胝体不同程度的发育不良,因此具有广泛的临床表现。本文描述了 1 例 15 岁男性,表现为发育迟缓及精神症状病史,偶然在磁共振成像上发现胼胝体脂肪瘤,提示临床相关性。