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慢性疾病背景下的执行功能与生存

Executive function and survival in the context of chronic illness.

机构信息

Departments of Kinesiology & Psychology, University of Waterloo, 200 University Avenue West, Waterloo, ON, Canada.

出版信息

Ann Behav Med. 2010 May;39(2):119-27. doi: 10.1007/s12160-010-9162-z.

Abstract

BACKGROUND

Individual differences in executive function (EF) have been shown to predict risk factors for chronic illness. It is not currently known whether EFs also predict survival time following a diagnosis of a chronic illness.

PURPOSE

The objective of this investigation was to examine the association between individual differences in EF and survival time among individuals suffering from one or more chronic illness.

METHODS

A sample of 162 community-dwelling older adults who suffered from a chronic illness at baseline underwent thorough medical and neurological examinations to ensure freedom from actual or probable dementia. Participants completed cognitive testing and were subsequently followed for 10 years; survival was assessed as survival time over the follow-up interval.

RESULTS

Findings indicated that individual differences in EF predicted survival time, and this association held when adjustments were made for demographic variables (age, sex), education, and body mass index.

CONCLUSION

Individual differences in EF may be important determinants of survival in the context of chronic illness.

摘要

背景

执行功能 (EF) 的个体差异已被证明可预测慢性疾病的危险因素。目前尚不清楚 EF 是否也可预测诊断出慢性疾病后的生存时间。

目的

本研究旨在探讨 EF 个体差异与患有一种或多种慢性疾病的个体的生存时间之间的关联。

方法

本研究纳入了 162 名基线时患有慢性疾病的社区居住的老年成年人,他们在进行全面的医学和神经学检查后,被排除了实际或可能的痴呆症。参与者完成了认知测试,并在随后的 10 年中进行了随访;将生存时间定义为随访期间的生存时间。

结果

研究结果表明,EF 的个体差异可预测生存时间,且当调整人口统计学变量(年龄、性别)、教育程度和体重指数后,这种关联仍然存在。

结论

EF 的个体差异可能是慢性疾病背景下生存的重要决定因素。

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