Department of Ophthalmology, Tokyo Medical University Hospital, Tokyo, Japan.
Jpn J Ophthalmol. 2010 Jan;54(1):19-23. doi: 10.1007/s10384-009-0759-3. Epub 2010 Feb 12.
To compare clinical findings in patients with ocular tuberculosis experienced during two different decades.
Thirty-four patients with ocular tuberculosis were divided into two groups: a 1990s group (n = 18) and a 2000s group (n = 16), according to the dates of their first outpatient visit. The clinical profiles of the two groups were then compared.
More cases of the 1990s group had complications involving extraocular tuberculosis than those of the 2000s group. While various ophthalmic manifestations were observed clinically in the 1990s group, all retinal periphlebitis cases presented in the 2000s group. The proportion of patients who received antituberculous treatment was higher in the 1990s group, but the proportion who received oral corticosteroid therapy did not differ between the two periods. However, more patients underwent laser photocoagulation in the 2000s group. The percentage of eyes with final visual acuity better than 20/20 increased in the 2000s group.
The clinical outcome of patients with ocular tuberculosis was improved in the 2000s group, which may be attributable to the increase in active use of laser photocoagulation therapy.
比较两个不同十年间眼部结核患者的临床发现。
根据首次门诊就诊日期，将 34 例眼部结核患者分为 1990 年代组（n = 18）和 2000 年代组（n = 16）。然后比较两组的临床特征。
1990 年代组中涉及眼外结核并发症的病例比 2000 年代组多。虽然 1990 年代组的各种眼部表现均有临床观察，但所有视网膜血管炎病例均出现在 2000 年代组。1990 年代组接受抗结核治疗的患者比例较高，但两个时期接受口服皮质类固醇治疗的患者比例无差异。然而，2000 年代组中有更多患者接受了激光光凝治疗。2000 年代组最终视力好于 20/20 的眼比例增加。
2000 年代组眼部结核患者的临床结局得到改善，这可能归因于激光光凝治疗的积极应用增加。
