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滥用一氧化二氮导致周围神经病。

Peripheral neuropathy following nitrous oxide abuse.

机构信息

Department of Emergency Medicine, Royal Brisbane & Women's Hospital, Butterfield St., Herston, Brisbane, QLD 4029, Australia.

出版信息

Emerg Med Australas. 2010 Feb;22(1):88-90. doi: 10.1111/j.1742-6723.2009.01262.x.

DOI:10.1111/j.1742-6723.2009.01262.x
PMID:20152009
Abstract

Undifferentiated neurological presentations are not uncommon to the ED. Vitamin B (12) deficiency can lead to progressive demyelination and axonal lesions on the peripheral nerves and cervicothoracic spinal cord causing a peripheral neuropathy. Nitrous oxide is a common adjuvant to anaesthesia in the ED but it not often thought of as a drug of abuse. A case is reported of prolonged and intensive nitrous oxide abuse that resulted in the development of a peripheral neuropathy.

摘要

神经内科急症中,非特异性神经表现并不少见。维生素 B12 缺乏可导致外周神经和颈胸段脊髓脱髓鞘和轴索病变,引起周围神经病。一氧化二氮是急诊科麻醉的常用辅助剂,但通常不被认为是一种滥用药物。本文报告了一例长期、大量滥用一氧化二氮导致周围神经病的病例。

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