氧化亚氮所致脊髓神经病。

Nitrous oxide-induced myeloneuropathy.

作者信息

Lunsford J M, Wynn M H, Kwan W H

出版信息

J Foot Surg. 1983 Fall;22(3):222-5.

Abstract

A disabling peripheral myeloneuropathy developed in a health professional with a history of chronic exposure and abuse of nitrous oxide. The distinctive clinical symptoms were radicular sensory loss rather than purely distal, and a "reverse" Lhermitte's sign in the absence of signs of specific spinal cord involvement. The entity of nitrous oxide-induced myeloneuropathy is discussed with a review of the literature, as well as present information regarding the etiology, pathophysiology, symptoms, and treatment. In addition, a case report of nitrous oxide-induced myeloneuropathy is presented.

摘要

一名有慢性一氧化二氮接触和滥用史的健康专业人员患上了致残性周围性脊髓神经病。其独特的临床症状为神经根性感觉丧失而非单纯的远端感觉丧失，且在无特定脊髓受累体征的情况下出现“反向”莱尔米特征。本文结合文献综述讨论了一氧化二氮诱导的脊髓神经病这一病症，以及目前有关其病因、病理生理学、症状和治疗的信息。此外，还呈现了一例一氧化二氮诱导的脊髓神经病的病例报告。