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在社区环境中进行的HIV非侵入性(口腔液)检测试点。

Pilot of non-invasive (oral fluid) testing for HIV within a community setting.

作者信息

Birrell Frances, Staunton Shaun, Debattista Joseph, Roudenko Nicole, Rutkin William, Davis Craig

机构信息

Communicable Diseases Branch, Queensland Health, Herston, Qld, Australia.

出版信息

Sex Health. 2010 Mar;7(1):11-6. doi: 10.1071/SH09029.

DOI:10.1071/SH09029
PMID:20152090
Abstract

BACKGROUND

The present study sought to determine the level of undiagnosed HIV infection within a community setting of men who have sex with men (MSM) and identify any associated sexual risk behaviours.

METHODS

A total of 427 MSM were recruited in sex-on-premises venues (SOPV) and gay bars within the inner city of Brisbane. An additional 37 MSM were recruited in a smaller, regional centre (Toowoomba). Oral fluid testing for HIV antibodies was undertaken using the Orasure collection system and assay. Each participant was invited to complete a brief behaviour questionnaire and submit an oral fluid specimen. Confirmed serology results were linked to reported sexual behaviours, testing patterns and HIV status.

RESULTS

Of the 464 men surveyed, 33 identified as HIV-positive, and all of these were reactive by the Orasure assay. A further eight people who identified as negative or unknown serostatus, had confirmed Orasure reactive results, resulting in 1.9% of the 'non-HIV positive' MSM sample unaware of their positive HIV status. Therefore, 19.5% of the total confirmed HIV-positive individuals were not aware of their true serostatus.

CONCLUSIONS

A significant minority of HIV-positive MSM are currently unaware of their positive serostatus. However, an analysis of their risk behaviour does not seem to indicate any significant difference to those who are HIV-negative. Interestingly, 86% of those who were unaware they were HIV-positive identified that they had been tested in the previous 6 months and all of them claimed to have been tested in the previous 2 years.

摘要

背景

本研究旨在确定男男性行为者(MSM)社区环境中未被诊断出的HIV感染水平,并识别任何相关的性风险行为。

方法

在布里斯班市中心的营业性性行为场所(SOPV)和同性恋酒吧招募了总共427名男男性行为者。另外37名男男性行为者在一个较小的地区中心(图文巴)招募。使用OraSure采集系统和检测方法进行HIV抗体的口腔液检测。邀请每位参与者完成一份简短的行为问卷并提交一份口腔液样本。将确认的血清学结果与报告的性行为、检测模式和HIV状态相关联。

结果

在接受调查的464名男性中,33人被确定为HIV阳性,并且所有这些人通过OraSure检测均呈反应性。另外8名自我认定为阴性或血清学状态未知的人,其OraSure检测结果呈阳性,导致1.9%的“非HIV阳性”男男性行为者样本不知道自己HIV检测呈阳性。因此,在所有确认的HIV阳性个体中,19.5%不知道自己的真实血清学状态。

结论

目前有相当一部分HIV阳性的男男性行为者不知道自己的血清学阳性状态。然而,对他们的风险行为分析似乎并未表明与HIV阴性者有任何显著差异。有趣的是,那些不知道自己HIV呈阳性的人中有86%表示他们在过去6个月内进行过检测,并且他们所有人都声称在过去2年内进行过检测。

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