兴奋性神经调质可减少多巴胺释放，增强催乳素分泌。
Excitatory neuromodulator reduces dopamine release, enhancing prolactin secretion.
机构信息
Department of Neurosurgery, Yale University, New Haven, CT 06520, USA.
出版信息
Neuron. 2010 Jan 28;65(2):147-9. doi: 10.1016/j.neuron.2010.01.013.
Abstract
Hypothalamic dopamine neurons inhibit pituitary prolactin secretion. In this issue of Neuron, Lyons et al. provide evidence for a novel model, whereby the excitatory neuropeptide TRH depolarizes gap-junction-coupled dopamine neurons, leading to a shift in the population pattern of action potentials from phasic burst firing to regular tonic firing, hypothetically reducing dopamine release while increasing total spike number.
摘要
下丘脑多巴胺神经元抑制垂体催乳素分泌。在本期《神经元》杂志上，Lyons 等人提供了一个新模型的证据，即兴奋性神经肽 TRH 使缝隙连接耦联的多巴胺神经元去极化，导致动作电位群体模式从相位爆发式放电转变为规则持续放电，假设减少多巴胺释放，同时增加总尖峰数。
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本文引用的文献
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