Department of Cancer Biology, Vanderbilt University, Nashville, TN 37232, USA.
Dev Cell. 2010 Jan 19;18(1):3-4. doi: 10.1016/j.devcel.2010.01.003.
Matrix metalloproteinases are well known for their key roles in the processing of extracellular matrix and nonmatrix molecules. Recently, a new theme of proteolysis-independent roles for metalloproteinases has emerged, with a paper from Gonzalo et al. in this issue of Developmental Cell providing an illustration.
基质金属蛋白酶以其在细胞外基质和非基质分子加工中的关键作用而闻名。最近,基质金属蛋白酶出现了一种新的非蛋白水解作用的主题,Gonzalo 等人在本期《发育细胞》杂志上发表的一篇论文提供了一个例证。