Department of Environmental Chemistry, Institute of Environmental Assessment and Water Research (IDAEA-CSIC), Jordi Girona 18-26, 08034 Barcelona, Catalonia, Spain.
Anal Chim Acta. 2010 Mar 3;662(1):23-30. doi: 10.1016/j.aca.2009.12.040. Epub 2010 Jan 11.
A method for the estimation of the human intake of trihalomethanes (THMs), namely chloroform, bromodichloromethane, dibromochloromethane and bromoform, during showering and bathing is reported. The method is based on the determination of these compounds in exhaled breath that is collected by solid adsorption on Tenax using a device specifically designed for this purpose. Instrumental measurements were performed by automatic thermal desorption coupled to gas chromatography with electron capture detection. THMs in exhaled breath samples were determined during showering and swimming pool attendance. The levels of these compounds in indoor air and water were also determined as reference for interpretation of the exhaled breath results. The THM concentrations in exhaled breath of the volunteers measured before the exposure experiments showed a close correspondence with the THMs levels in indoor air where the sampler was located. Limits of detection in exhaled breath were dependent on THM analytes and experimental sites. They ranged between 170 and 710 ng m(-3) in the swimming pool studies and between 97 and 460 ng m(-3) in the showering studies. Application of this method to THMs determination during showering and swimming pool activities revealed statistically significant increases in THMs concentrations when comparing exhaled breath before and after exposure.
本文报道了一种用于估算人体在淋浴和沐浴时摄入三卤甲烷（THMs），即氯仿、一溴二氯甲烷、二溴一氯甲烷和溴仿的方法。该方法基于通过使用专门为此目的设计的装置，通过固体吸附在 Tenax 上收集呼出的呼吸中的这些化合物来进行。仪器测量通过自动热解吸与带有电子捕获检测的气相色谱法自动进行。在淋浴和游泳池游泳时，对呼出呼吸样本中的 THMs 进行了测定。还确定了室内空气和水中这些化合物的水平，作为解释呼出呼吸结果的参考。在暴露实验之前测量的志愿者呼出呼吸中的 THM 浓度与采样器所在的室内空气中的 THMs 水平密切对应。呼出呼吸中的检出限取决于 THM 分析物和实验地点。在游泳池研究中，它们的范围在 170 到 710ngm(-3)之间，在淋浴研究中，它们的范围在 97 到 460ngm(-3)之间。将该方法应用于测定淋浴和游泳池活动期间的 THMs 表明，与暴露前相比，暴露后 THMs 浓度有统计学意义上的增加。
