Imaging services, Royal Perth Hospital, Perth, WA 6847, Australia.
Clin Radiol. 2010 Mar;65(3):198-205. doi: 10.1016/j.crad.2009.09.015. Epub 2010 Jan 22.
To investigate whether remodelling of the breast after breast reduction surgery has an effect on mammographic cancer detection.
For women who attended population-based screening between January 1998 to December 2007, data were extracted on their age, history of previous breast reduction, and the result of screening (recall for further assessment, cancer, or no cancer). The number of cancers detected, recalls per 1000 screens and the characteristics of the cancers detected in the two groups was compared.
In total 244,147 women with 736,219 screening episodes were reviewed. In the 4743 women who had a breast reduction, 51 breast cancers were detected [age standardized rate (ASR) of 4.28 per 1000 screening episodes; 95% CI 3.11-5.46], compared with 4342 breast cancers in 239 404 women screened in the non-reduction group (ASR of 5.99 per 1000 screening episodes; 95% CI 5.81-6.16). There were fewer cancers in the breast reduction group with a relative risk of 0.71. There was no significant difference in the rate of recall between the two groups, with a crude recall rate of 46.1 per 1000 screening episodes post-breast reduction compared with 50.7 per 1000 screening episodes for women without breast reduction. There was no significant difference in the pathological type or location of the cancer between the two groups of women.
Postoperative breast changes following reduction mammoplasty do not significantly hinder analysis of the screening mammogram.
探讨乳房缩小术后乳房重塑是否会影响乳腺钼靶检查的癌症检出率。
对 1998 年 1 月至 2007 年 12 月期间参加人群筛查的女性,提取其年龄、既往乳房缩小术史以及筛查结果(召回进一步评估、癌症或无癌症)的数据。比较两组中检出的癌症数量、每千例筛查召回率以及检出癌症的特征。
共回顾了 244147 名女性的 736219 次筛查期。在 4743 名接受乳房缩小术的女性中,检出 51 例乳腺癌[年龄标准化检出率(ASR)为每千例筛查期 4.28 例;95%可信区间(95%CI)为 3.11-5.46],而在未接受乳房缩小术的 239404 名女性的筛查中,检出 4342 例乳腺癌[ASR 为每千例筛查期 5.99 例;95%CI 为 5.81-6.16]。缩小组的癌症数量较少,相对风险为 0.71。两组间召回率无显著差异,乳房缩小术后的粗召回率为每千例筛查期 46.1 例,而未接受乳房缩小术的女性为每千例筛查期 50.7 例。两组女性的癌症病理类型或部位无显著差异。
乳房缩小成形术后的乳房变化不会显著影响乳腺钼靶检查的分析。