Department of Psychiatry, Gil Medical Center, Gachon University of Medicine and Science, Incheon 405-760, South Korea.
Compr Psychiatry. 2010 Mar-Apr;51(2):165-70. doi: 10.1016/j.comppsych.2009.05.004. Epub 2009 Jul 9.
Depressive symptoms are common in schizophrenia and are considered core features of the disorder. The purpose of the present study was to examine the relationship between depressive symptoms and subjective well-being in newly admitted patients with schizophrenia.
Eighty newly admitted patients were comprehensively evaluated for subjective well-being, schizophrenic symptoms, and depressive symptoms using the Subjective Well-Being Under Neuroleptics Scale (SWN), the Positive and Negative Syndrome Scale (PANSS), and the Beck Depression Inventory. Correlation coefficients were obtained between depressive symptoms and subjective well-being while controlling for the influence of the severity of psychotic symptoms, extrapyramidal side effect, and subjective attitude toward antipsychotics, as assessed by the PANSS, the Drug-Induced Extrapyramidal Symptoms Scale, and the Drug Attitude Inventory, respectively.
The SWN score had a significant negative correlation with the PANSS depression factor score (P < .001). Correlation analysis also revealed a significant negative correlation between the SWN score and the Beck Depression Inventory score (P < .001).
The results of our study suggest that depressive symptoms are significantly associated with a low subjective well-being in newly admitted patients with schizophrenia and that the relationship is significant even after controlling for the influence of potential confounding variables. Detection and appropriate management of depressive symptoms in schizophrenic patients may affect their perceptions of their own well-being.
抑郁症状在精神分裂症中很常见,被认为是该疾病的核心特征。本研究的目的是探讨新入院精神分裂症患者抑郁症状与主观幸福感之间的关系。
使用主观幸福感在神经阻滞剂下量表(SWN)、阳性和阴性症状量表(PANSS)和贝克抑郁量表(BDI),对 80 名新入院的患者进行全面评估,以评估主观幸福感、精神分裂症症状和抑郁症状。在控制精神病症状严重程度、锥体外系副作用和对精神药物的主观态度的影响后,通过 PANSS、药物诱导的锥体外系症状量表和药物态度量表分别评估,获得抑郁症状与主观幸福感之间的相关系数。
SWN 评分与 PANSS 抑郁因子评分呈显著负相关(P<0.001)。相关分析还显示 SWN 评分与 BDI 评分呈显著负相关(P<0.001)。
本研究结果表明,抑郁症状与新入院精神分裂症患者的低主观幸福感显著相关,即使在控制潜在混杂变量的影响后,这种关系仍然显著。在精神分裂症患者中检测和适当管理抑郁症状可能会影响他们对自身幸福感的感知。