实时三维超声心动图对右心室容量和功能的动态评估：与 100 例成人患者磁共振成像的对比研究。
Dynamic assessment of right ventricular volumes and function by real-time three-dimensional echocardiography: a comparison study with magnetic resonance imaging in 100 adult patients.
机构信息
Department of Cardiology, University Hospital Basel, Basel, Switzerland.
出版信息
J Am Soc Echocardiogr. 2010 Feb;23(2):116-26. doi: 10.1016/j.echo.2009.11.016.
BACKGROUND
The aim of this study was to validate a novel real-time three-dimensional echocardiographic (RT3DE) analysis tool for the determination of right ventricular volumes and function in unselected adult patients.
METHODS
A total of 100 consecutive adult patients with normal or pathologic right ventricles were enrolled in the study. A dynamic polyhedron model of the right ventricle was generated using dedicated RT3DE software. Volumes and ejection fractions were determined and compared with results obtained on magnetic resonance imaging (MRI) in 88 patients with adequate acquisitions.
RESULTS
End-diastolic, end-systolic, and stroke volumes were slightly lower on RT3DE imaging than on MRI (124.0 +/- 34.4 vs 134.2 +/- 39.2 mL, P < .001; 65.2 +/- 23.5 vs 69.7 +/- 25.5 mL, P = .02; and 58.8 +/- 18.4 vs 64.5 +/- 24.1 mL, P < .01, respectively), while no significant difference was observed for ejection fraction (47.8 +/- 8.5% vs 48.2 +/- 10.8%, P = .57). Correlation coefficients on Bland-Altman analysis were r = 0.84 (mean difference, 10.2 mL; 95% confidence interval [CI], -31.3 to 51.7 mL) for end-diastolic volume, r = 0.83 (mean difference, 4.5 mL; 95% CI, -23.8 to 32.9 mL) for end-systolic volume, r = 0.77 (mean difference, 5.7 mL; 95% CI, -24.6 to 36.0 mL) for stroke volume, and r = 0.72 (mean difference, 0.4%; 95% CI, -14.2% to 15.1%) for ejection fraction.
CONCLUSION
Right ventricular volumes and ejection fractions as assessed using RT3DE imaging compare well with MRI measurements. RT3DE imaging may become a time-saving and cost-saving alternative to MRI for the quantitative assessment of right ventricular size and function.
背景
本研究旨在验证一种新型实时三维超声心动图（RT3DE）分析工具，用于评估未经选择的成年患者的右心室容积和功能。
方法
本研究共纳入 100 例右心室正常或病变的成年患者。使用专用 RT3DE 软件生成右心室动态多面体模型。在 88 例采集充分的患者中，确定容积和射血分数，并与磁共振成像（MRI）结果进行比较。
结果
RT3DE 成像的右心室舒张末期、收缩末期和每搏量略低于 MRI（124.0 ± 34.4 比 134.2 ± 39.2 mL，P <.001；65.2 ± 23.5 比 69.7 ± 25.5 mL，P =.02；58.8 ± 18.4 比 64.5 ± 24.1 mL，P <.01），但射血分数无显著差异（47.8 ± 8.5%比 48.2 ± 10.8%，P =.57）。 Bland-Altman 分析的相关系数为：舒张末期容积 r = 0.84（平均差值，10.2 mL；95%置信区间[CI]，-31.3 至 51.7 mL），收缩末期容积 r = 0.83（平均差值，4.5 mL；95% CI，-23.8 至 32.9 mL），每搏量 r = 0.77（平均差值，5.7 mL；95% CI，-24.6 至 36.0 mL），射血分数 r = 0.72（平均差值，0.4%；95% CI，-14.2%至 15.1%）。
结论
使用 RT3DE 成像评估右心室容积和射血分数与 MRI 测量值具有良好的相关性。RT3DE 成像可能成为一种替代 MRI 进行右心室大小和功能定量评估的省时、省钱的方法。
Zotero 插件