Pôle d'Endocrinologie, Faculté de Médecine Pierre & Marie Curie -Paris 6 University-CNRH-IDF, AP-HP, Pitié-Salpêtrière, Paris, France.
Diabetes Metab. 2009 Dec;35(6 Pt 2):532-6. doi: 10.1016/S1262-3636(09)73462-7.
Obesity is the most important lifestyle-related risk factor for type 2 diabetes (T2DM). The prevalence of T2DM in adolescents is increasing in parallel with the increasing incidence of major obesity. In adult obese subjects, the greatest degree of T2DM prevention, improvement or recovery has been reported in patients who have undergone bariatric surgery. However, few studies are available on the benefits and risks of bariatric surgery in adolescents with T2DM. The indications for obesity surgery in this population are unusual, and should only be considered in academic settings after comprehensive interdisciplinary evaluation.
肥胖是 2 型糖尿病(T2DM)最重要的与生活方式相关的风险因素。随着主要肥胖症发病率的增加,青少年中的 T2DM 患病率也在增加。在成年肥胖患者中,接受减重手术的患者报告 T2DM 的预防、改善或恢复程度最大。然而,关于肥胖症手术在青少年 T2DM 患者中的益处和风险的研究很少。该人群肥胖症手术的适应证不常见,只有在经过全面的跨学科评估后,才应在学术环境中考虑。