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经支气管镜球囊扩张治疗气管支气管狭窄:长期随访。

Bronchoscopic balloon dilatation of tracheobronchial stenosis: long-term follow-up.

机构信息

Pulmonary Institute, Rabin Medical Center, Beilinson Campus, Petah Tikva, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

出版信息

Eur J Cardiothorac Surg. 2010 Aug;38(2):198-202. doi: 10.1016/j.ejcts.2009.11.056. Epub 2010 Feb 12.

Abstract

OBJECTIVES

Bronchoscopic balloon dilatation (BBD) has become a valuable tool in the treatment of tracheobronchial stenosis (TBS). The objective of this study was to assess the short- and long-term effects of BBD.

METHODS

A retrospective study that included all patients with confirmed, symptomatic stenosis, who underwent BBD between 2002 and 2008. A total of 92 BBD procedures were performed in 35 patients at our institute. Lung function studies were recorded for all patients before, immediately after and 1 month following the BBD. Long-term follow-up was for a mean of 33+/-4 months.

RESULTS

All patients had initial success, including increased airway dimensions and symptom relief. No complications were noted related to BBD. Forced expiratory volume after one second (FEV(1)) was significantly increased after BBD (10.5%, p=0.03). These effects persisted for at least 1 month. Long-term follow-up, however, demonstrated the need for stent placement in 25 of 35 patients (71%), 210+/-91 days after BBD. Ten of 35 patients died 456+/-119 days after BBD due to progression of primary disease; all deaths were unrelated to the BBD procedures.

CONCLUSIONS

BBD is a safe method that offers immediate symptomatic relief in both tracheal and bronchial stenosis. However, BBD is a temporary measure, as many patients will require definitive or additional treatment with laser or stent placement.

摘要

目的

支气管镜球囊扩张(BBD)已成为治疗气管支气管狭窄(TBS)的有价值的工具。本研究的目的是评估 BBD 的短期和长期效果。

方法

这是一项回顾性研究,纳入了 2002 年至 2008 年间在我院接受 BBD 治疗的所有确诊、有症状狭窄患者。共有 35 例患者共进行了 92 次 BBD 手术。所有患者均在 BBD 治疗前、治疗后立即和 1 个月后进行肺功能检查。长期随访平均为 33+/-4 个月。

结果

所有患者均获得初始成功,包括气道尺寸增加和症状缓解。BBD 无相关并发症。BBD 后 1 秒用力呼气量(FEV(1))显著增加(10.5%,p=0.03)。这些效果至少持续 1 个月。然而,长期随访显示,25/35 例(71%)患者在 BBD 后 210+/-91 天需要放置支架。35 例患者中有 10 例在 BBD 后 456+/-119 天因原发疾病进展而死亡;所有死亡均与 BBD 无关。

结论

BBD 是一种安全的方法,可立即缓解气管和支气管狭窄的症状。然而,BBD 是一种临时措施,因为许多患者需要通过激光或支架放置进行明确或额外的治疗。

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