Nakasu Yoko, Mitsuya Ko-ichi
Division of Neurosurgery, Shizuoka Cancer Center.
Gan To Kagaku Ryoho. 2010 Feb;37(2):204-10.
Metastatic brain tumors are increasingly important determinants of survival and quality of life in patients with cancer. The management of brain metastases is directed by prognostic factors, including the Karnofsky Performance Status, age, pathological diagnosis, number of brain metastases, and systemic condition. Most metastatic brain tumors are treated by surgery, radiosurgery, and/or whole brain radiation therapy. Adequate management strategy cannot be standardized to a single paradigm. Current diagnostic modalities and techniques are reviewed, and data of several clinical studies are presented to help physicians and surgeons make informed decisions about the benefits and risks of approaches.
转移性脑肿瘤日益成为癌症患者生存和生活质量的重要决定因素。脑转移瘤的治疗由预后因素指导,包括卡氏功能状态、年龄、病理诊断、脑转移瘤数量和全身状况。大多数转移性脑肿瘤通过手术、放射外科和/或全脑放射治疗进行治疗。适当的管理策略无法标准化为单一模式。本文综述了当前的诊断方法和技术,并展示了几项临床研究的数据,以帮助医生和外科医生就是否采用这些方法的益处和风险做出明智的决定。