Cook B L, Winokur G, Garvey M J, Beach V
University of Iowa College of Medicine, Iowa City.
Br J Psychiatry. 1991 Jan;158:72-5. doi: 10.1192/bjp.158.1.72.
A prospective study of male in-patients over 55 years old who met Feighner criteria for non-bipolar depression was performed to determine if a previous history of alcoholism significantly influenced treatment or response to treatment. Among 58 subjects with complete follow-up information, the 16 who had a history of alcoholism had a presentation at index which differed from that of the non-alcoholics, and on follow-up they clearly had more chronic illness. This elderly sample with alcoholism resembles 'neurotic-reactive' depressives described in younger samples, and supports a past history of alcoholism as being a risk factor for chronicity of depression on follow-up in the elderly population.
对符合费伊纳非双相抑郁标准的55岁以上男性住院患者进行了一项前瞻性研究,以确定既往酗酒史是否会显著影响治疗或治疗反应。在58名有完整随访信息的受试者中,16名有酗酒史的患者在初次就诊时的表现与非酗酒者不同,且在随访中他们明显患有更多慢性疾病。这个有酗酒问题的老年样本类似于年轻样本中描述的“神经症反应性”抑郁症患者,并支持既往酗酒史是老年人群随访中抑郁症慢性化的一个风险因素。