Feldman J M, Plonk J W
Horm Res. 1978;9(1):1-11. doi: 10.1159/000178891.
Three patients with hyperprolactinemia (2 with pituitary tumors and 1 with a hypothalamic disturbance) underwent evaluation of their hypothalamic-pituitary-adrenal axis using ACTH, metyrapone and in one case repetitive insulin tolerance tests. With the exception of a suggestion of a slight increase in adrenal responsiveness to pharmacological doses of ACTH in one of the patients, there was no alteration in the adrenal responsiveness of the 3 patients evaluated. We conclude that hyperprolactinemia probably does not systematically modify the responsiveness of the hypothalamic-pituitary-adrenal axis.
三名高催乳素血症患者（2例患有垂体瘤，1例患有下丘脑功能障碍）接受了使用促肾上腺皮质激素（ACTH）、甲吡酮的下丘脑-垂体-肾上腺轴评估，其中1例还进行了重复胰岛素耐量试验。除1例患者对药理剂量的ACTH肾上腺反应性略有增加外，其余3例患者的肾上腺反应性均无改变。我们得出结论，高催乳素血症可能不会系统性地改变下丘脑-垂体-肾上腺轴的反应性。
