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美沙酮维持治疗患者中的病理性赌博和强迫症。

Pathological gambling and obsessive compulsive disorder among methadone maintenance treatment patients.

机构信息

Dr. Miriam & Sheldon G. Adelson Clinic for Drug Abuse, Treatment & Research, Tel-Aviv, Israel.

出版信息

J Addict Dis. 2009 Jul;28(3):199-207. doi: 10.1080/10550880903014106.

Abstract

The aims of this study was to assess the prevalence of lifetime pathological gambling (pathological gambling) and current obsessive compulsive disorder among former heroin addicts currently in methadone maintenance treatment. A cross-sectional study of 154 patients from a methadone maintenance treatment clinic affiliated of a tertiary-referral medical center was conducted. The South Oaks Gambling Screen and Yale-Brown Obsessive Compulsive Scale were used for measurement purposes. Lifetime pathological gambling was found in 45 (29.2%) patients (current pathological gambling was found in 10 [6.5%] patients). Clinical obsessive compulsive disorder (defined if scored as moderate to extreme) was found in 51.1% of patients in the pathological gambling groups and 39.4% of patients in the non-pathological gambling group, with higher obsessive scores in the pathological gambling group versus the non-pathological gambling group. Logistic regression (multivariate analyses) found pathological gambling in more males (odds ratio = 3.6, 95% confidence interval = 1.5-8.8), a high obsessive score (odds ratio = 1.07, 95% confidence interval = 0.1-1.1), and older age on admission (40 years and older) (odds ratio = 2.4, 95% confidence interval = 1.1-5.0). Because only 10 (6.5%) patients were still currently gambling, more urgent intervention should be considered to the unexpected high rate of clinical obsessive-compulsive disorder (42.9%) in the sample, possibly because the clinic studied is of a higher severity than that accepted to the methadone maintenance treatment clinics in the community.

摘要

这项研究的目的是评估目前正在美沙酮维持治疗的前海洛因成瘾者终身病态赌博(病态赌博)和当前强迫症的患病率。对隶属于三级转诊医疗中心的美沙酮维持治疗诊所的 154 名患者进行了横断面研究。使用 South Oaks 赌博筛查量表和 Yale-Brown 强迫量表进行测量。发现 45 名患者(29.2%)有终身病态赌博(发现 10 名患者有当前病态赌博[6.5%])。在病态赌博组中,51.1%的患者存在临床强迫症(定义为中度至重度),而非病态赌博组中,39.4%的患者存在临床强迫症,病态赌博组的强迫得分高于非病态赌博组。逻辑回归(多变量分析)发现,病态赌博与更多男性(优势比=3.6,95%置信区间=1.5-8.8)、高强迫评分(优势比=1.07,95%置信区间=0.1-1.1)和入院时年龄较大(40 岁及以上)(优势比=2.4,95%置信区间=1.1-5.0)有关。由于只有 10 名患者(6.5%)仍在赌博,因此应该考虑对样本中意外出现的高比例临床强迫障碍(42.9%)进行更紧急的干预,这可能是因为研究的诊所比社区美沙酮维持治疗诊所的严重程度更高。

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