Mayo Clinic and Foundation, Rochester, MN 55905, USA.
J Addict Dis. 2009 Jul;28(3):243-9. doi: 10.1080/10550880903014205.
This article aims at identifying a threshold number of drinks per day beyond which there is a high risk of developing alcoholic behavior that would enable physicians to more confidently support the use of alcohol for cardiovascular risk prevention. In a randomly selected, population-based sample of 2,042 adults 45 years or older, we graded alcohol drinking behavior using the Self-Administered Alcoholism Screening Test, quantified alcohol amount by questionnaire, and assessed the prevalence of cardiovascular disease (coronary, peripheral, or cerebrovascular disease) by medical record review. Although optimal alcohol use (< or = 2 drinks/day) was associated with reduced odds of cardiovascular disease, 43% of alcoholics and 82% of problem drinkers reported alcohol use in the optimal range as well. The association of alcohol use in the optimal range with alcohol-related behavioral problems supports the reluctance in physicians from recommending alcohol use for cardiovascular benefit, not withstanding the underreporting of alcohol use by alcoholics.
本文旨在确定一个每日饮酒量的阈值,超过这个阈值,就会有很高的风险出现酗酒行为,从而使医生更有信心地支持用饮酒来预防心血管疾病。在一个随机抽取的、年龄在 45 岁或以上的 2042 名成年人的基于人群的样本中,我们使用自我管理的酒精使用障碍筛查测试来评估饮酒行为,通过问卷调查来量化饮酒量,并通过病历回顾来评估心血管疾病(冠状动脉、外周或脑血管疾病)的患病率。尽管适量饮酒(<或=2 杯/天)与降低心血管疾病的几率有关,但 43%的酗酒者和 82%的有问题饮酒者也报告了在这个最佳范围内的饮酒。在最佳范围内饮酒与与酒精相关的行为问题有关,这支持了医生不愿推荐饮酒来预防心血管疾病的做法,尽管酗酒者会少报饮酒量。