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头颈部坏死性筋膜炎:两例报告及文献综述

Necrotizing fasciitis of the head and neck: Report of two cases and literature review.

作者信息

Oguz Haldun, Demirci Munir, Arslan Necmi, Safak Mustafa Asim, Paksoy Gulcihan

机构信息

Department of Otolaryngology, Ankara Training and Research Hospital, Turkey.

出版信息

Ear Nose Throat J. 2010 Feb;89(2):E7-10.

Abstract

Necrotizing fasciitis (NF) is a potentially fatal soft-tissue infection characterized by rapidly progressive necrosis of subcutaneous tissue and superficial fascia. NF of the head and neck is a rare clinical entity, and it must be carefully differentiated from less severe conditions. Factors such as delayed treatment, inappropriate treatment, host debilitation, and polymicrobial infection contribute to the mortality and morbidity of NF. Adequate surgical debridement, urgent antibiotic therapy, and supportive measures are the keys to decreasing mortality and morbidity. We report 2 new cases and review the literature.

摘要

坏死性筋膜炎(NF)是一种潜在的致命性软组织感染,其特征为皮下组织和浅筋膜迅速进行性坏死。头颈部坏死性筋膜炎是一种罕见的临床病症,必须仔细与病情较轻的情况相鉴别。治疗延迟、治疗不当、宿主衰弱及混合细菌感染等因素会导致坏死性筋膜炎的死亡率和发病率上升。充分的手术清创、紧急抗生素治疗及支持措施是降低死亡率和发病率的关键。我们报告2例新病例并对文献进行综述。

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