Levy Jaime, Lifshitz Tova
Department of Ophthalmology, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Eur J Ophthalmol. 2010 Jul-Aug;20(4):780-4. doi: 10.1177/112067211002000422.
The majority of reported cases of infectious keratitis after intrastromal corneal ring segment implantation have been described after mechanical implantation of the segments. We present a case of keratitis after implantation of intrastromal corneal ring segments (Intacs) aided by femtosecond laser for keratoconus correction and review the relevant literature.
A 31-year-old woman with keratoconus underwent uneventful sequential implantation of intrastromal corneal ring segments (Intacs) aided by femtosecond laser performed 6 weeks apart. Two months after surgery in the second eye, she complained of red eye, pain, and decreased vision of 2 days' duration. Left eye visual acuity was 20/100.
Slit-lamp examination of the left eye revealed a stromal infiltrate at the lower segment near the incision site. The infiltrate progressed despite topical treatment of vancomycin and ceftazidime. Cultures were negative. The inferior segment was removed and the inferior channel irrigated with antibiotics. One day later significant fibrin and 1-mm hypopyon were detected in the anterior chamber Significant improvement was observed after adding topical amikacin and amphotericin B. Six months later, a small stromal scar is present at the inferior incision site and best-corrected visual acuity is 20/25.
To our knowledge, this is the second reported case of keratitis after implantation of intrastromal corneal ring segments (Intacs) aided by femtosecond laser for keratoconus correction. Prompt and adequate treatment is essential to prevent irreversible reduction of visual acuity.
大多数报道的角膜基质内环形植片植入术后感染性角膜炎病例是在机械植入植片后发生的。我们报告一例在飞秒激光辅助下植入角膜基质内环形植片(Intacs)治疗圆锥角膜后发生角膜炎的病例,并复习相关文献。
一名31岁圆锥角膜女性患者在飞秒激光辅助下顺利地分两次、间隔6周进行了角膜基质内环形植片(Intacs)植入。第二只眼手术后两个月,她主诉眼红、疼痛,视力下降2天。左眼视力为20/100。
裂隙灯检查发现左眼切口部位下方角膜基质有浸润。尽管局部使用万古霉素和头孢他啶治疗,浸润仍进展。培养结果为阴性。取出下方植片,并用抗生素冲洗下方植片通道。一天后,前房内发现大量纤维素和1毫米积脓。加用局部阿米卡星和两性霉素B后观察到明显改善。六个月后,下方切口部位有一个小的角膜基质瘢痕,最佳矫正视力为20/25。
据我们所知,这是第二例报道的在飞秒激光辅助下植入角膜基质内环形植片(Intacs)治疗圆锥角膜后发生角膜炎的病例。及时、充分的治疗对于防止视力不可逆下降至关重要。