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角膜内环植入术后耐甲氧西林金黄色葡萄球菌性急性角膜炎

Methicillin-Resistant Staphylococcus aureus Acute Keratitis After Intracorneal Ring Segment Implantation.

作者信息

García de Oteyza Gonzalo, Laiseca Andrea, Sauvageot Paola, Álvarez de Toledo Juan

机构信息

Department of Cornea and Ocular Surface, Centro de Oftalmología Barraquer, Barcelona, Spain.

出版信息

Ophthalmol Ther. 2017 Dec;6(2):367-371. doi: 10.1007/s40123-017-0103-9. Epub 2017 Aug 14.

DOI:10.1007/s40123-017-0103-9
PMID:28808911
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5693820/
Abstract

INTRODUCTION

The purpose of this study was to report the first case of acute bacterial keratitis produced by methicillin-resistant Staphylococcus aureus after the implantation of two intracorneal ring segments during an uneventful procedure for treating keratoconus in a 13-year-old child.

CASE REPORT

A patient with grade III keratoconus underwent an implantation of intracorneal ring segments with no complications during the procedure. Three days later, a whitish corneal infiltrate appeared in between the union of both corneal rings. Sample cultures were positive for methicillin-resistant S. aureus (MRSA). Corneal infiltrate did not improve despite intensive topical and systemic antibiotics. Melting appeared even after the explantation of both corneal rings. Keratoplasty à chaud had to be performed to preserve the eye integrity.

CONCLUSIONS

MRSA keratitis following intracorneal ring segment implantation is a rare but severe complication that can lead to a therapeutic penetrating keratoplasty to definitely cure the process.

摘要

引言

本研究的目的是报告首例在一名13岁儿童治疗圆锥角膜的手术过程顺利、植入两枚角膜内环后发生的耐甲氧西林金黄色葡萄球菌所致急性细菌性角膜炎病例。

病例报告

一名患有III级圆锥角膜的患者在手术过程中植入角膜内环,未出现并发症。三天后,在两枚角膜环结合处之间出现白色角膜浸润。样本培养显示耐甲氧西林金黄色葡萄球菌(MRSA)呈阳性。尽管使用了强化的局部和全身抗生素,角膜浸润仍未改善。即使在两枚角膜环取出后仍出现角膜溶解。必须进行热角膜移植以维持眼球完整性。

结论

角膜内环植入后发生的MRSA角膜炎是一种罕见但严重的并发症,可导致治疗性穿透性角膜移植以彻底治愈该病症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7128/5693820/c84ae77f0a2e/40123_2017_103_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7128/5693820/f9bb9bd91187/40123_2017_103_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7128/5693820/5693b7c3f3d4/40123_2017_103_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7128/5693820/c84ae77f0a2e/40123_2017_103_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7128/5693820/f9bb9bd91187/40123_2017_103_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7128/5693820/5693b7c3f3d4/40123_2017_103_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7128/5693820/c84ae77f0a2e/40123_2017_103_Fig3_HTML.jpg

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本文引用的文献

1
Microbial keratitis after intrastromal corneal ring segment implantation.基质内角膜环段植入术后的微生物性角膜炎。
J Refract Surg. 2010 May;26(5):364-9. doi: 10.3928/1081597X-20090617-06. Epub 2010 May 19.
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Causes of intrastromal corneal ring segment explantation: clinicopathologic correlation analysis.基质内角膜环段取出的原因:临床病理相关性分析。
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Keratitis after implantation of intrastromal corneal ring segments (intacs) aided by femtosecond laser for keratoconus correction: case report and description of the literature.
飞秒激光辅助下植入角膜基质内环形片(Intacs)矫正圆锥角膜后发生的角膜炎:病例报告及文献描述
Eur J Ophthalmol. 2010 Jul-Aug;20(4):780-4. doi: 10.1177/112067211002000422.
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Complications of intrastromal corneal ring segment implantation using a femtosecond laser for channel creation: a survey of 850 eyes with keratoconus.基质内角膜环段植入术使用飞秒激光创建通道的并发症:圆锥角膜 850 眼调查。
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Corneal infections after implantation of intracorneal ring segments.角膜内环植入术后的角膜感染
Cornea. 2004 Aug;23(6):547-9. doi: 10.1097/01.ico.0000126434.95325.24.
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Late bacterial keratitis after implantation of intrastromal corneal ring segments.基质内角膜环植入术后迟发性细菌性角膜炎
J Cataract Refract Surg. 2003 Feb;29(2):407-9. doi: 10.1016/s0886-3350(02)01484-0.
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Therapeutic keratoplasty for infectious keratitis: a review of the literature.感染性角膜炎的治疗性角膜移植术:文献综述
CLAO J. 2002 Jul;28(3):111-8.
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