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儿童眼部毛细血管血管瘤治疗后的视觉结果:10 年回顾。

Visual outcomes of treated periocular capillary haemangiomas in childhood: a 10-year review.

机构信息

Department of Ophthalmology, Royal Victoria Hospital, Belfast, BT12 6BA, Northern Ireland, UK.

出版信息

Acta Ophthalmol. 2011 Jun;89(4):396-401. doi: 10.1111/j.1755-3768.2009.01789.x. Epub 2010 Feb 12.

Abstract

PURPOSE

To report our experiences of treating periocular capillary haemangioma with particular emphasis on visual outcomes.

METHODS

Patients who underwent treatment for periocular capillary haemangioma were identified, and a chart review was performed.

RESULTS

There were seventeen patients in the study. The main indications for treatment were increased size of lesion with threat of amblyopia and partial or full pupil occlusion. Seven patients required more than one type of treatment. Fourteen patients had intralesional steroid treatment and six patients had oral steroids. Intralesional steroids gave variable results with minimal side-effects, oral steroids were very effective but 4 out of 6 patients developed side-effects. The average pretreatment astigmatism was 2.4D and post treatment this had reduced to 1.3D. Final visual outcomes were available for 15 patients, 13 had visual acuity of 6/7.5 or better, two were amblyopic with vision of 6/9-2 and 6/18.

CONCLUSION

In this study, intralesional steroids were used for localized lesions and oral steroids for diffuse haemangiomas with orbital involvement. Treatment especially with oral steroids was found to halt the proliferative phase and assist early haemangioma regression reducing ocular sequelae.

摘要

目的

报告我们在治疗眼部毛细血管血管瘤方面的经验,特别强调视觉结果。

方法

确定接受眼部毛细血管血管瘤治疗的患者,并进行图表回顾。

结果

研究中有 17 名患者。治疗的主要指征是病变增大,伴有弱视威胁和部分或全部瞳孔阻塞。7 名患者需要不止一种治疗方法。14 名患者接受了病灶内类固醇治疗,6 名患者接受了口服类固醇治疗。病灶内类固醇治疗效果不一,副作用最小,口服类固醇非常有效,但 6 名患者中有 4 名出现副作用。平均术前散光为 2.4D,治疗后降低至 1.3D。15 名患者的最终视力结果可用,其中 13 名视力为 6/7.5 或更好,2 名弱视患者视力分别为 6/9-2 和 6/18。

结论

在这项研究中,病灶内类固醇用于局限性病变,口服类固醇用于弥漫性血管瘤合并眼眶受累。发现治疗,特别是口服类固醇治疗,可阻止增生期并有助于早期血管瘤消退,减少眼部后遗症。

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