Bek Dorte, Kjeldsen Marianne Kirstine, Kamper-Jørgensen Zaza, Hansen Nikolaj Friis, Rasmussen Erik Michael
Mykobakteriologisk Laboratorium, Statens Serum Institut, DK-2300 København S, Denmark.
Ugeskr Laeger. 2010 Feb 15;172(7):549-50.
Tuberculosis (TB) is caused by pathogenic species within the Mycobacterium tuberculosis complex (MTBC). In the present case, a 40-year-old African man was admitted acutely. Despite negative microscopy, anti-TB treatment was initialized. Thirteen hours after hospitalisation, the patient suffered circulatory failure and died. Post mortem material from the lungs and pericardia tested positive for MTBC and was identified as Mycobacterium africanum by a new molecular method that enables identification of six of the eight MTBC species and provides clinicians with species-specific results.
结核病（TB）由结核分枝杆菌复合群（MTBC）中的致病菌种引起。在本病例中，一名40岁的非洲男子急性入院。尽管显微镜检查结果为阴性，但仍开始进行抗结核治疗。住院13小时后，患者出现循环衰竭并死亡。通过一种新的分子方法对肺和心包的尸检材料进行检测，结果显示MTBC呈阳性，并被鉴定为非洲分枝杆菌，该方法能够鉴定出8种MTBC菌种中的6种，并为临床医生提供菌种特异性结果。
