Department of Lung Diseases and Tuberculosis,Medical University of Bialystok, Bialystok, Poland.
Eur J Med Res. 2009 Dec 7;14 Suppl 4(Suppl 4):162-4. doi: 10.1186/2047-783x-14-s4-162.
A 61-year-old Caucasian was admitted to Department of Chest Diseases and Tuberculosis, Medical University of Bialystok, Poland for progressive muscle weakness and weight loss. Eighteen months prior to admission, the patient had been diagnosed with pulmonary embolism. At that point he was started on Enoxaparin QD. Past medical history was unremarkable. In the interim, the patient developed fever, myalgia and progressive dyspnea. Physical examination on admission revealed a rash on his upper torso and back, and the extensor surfaces of all four extremities. Laboratory values included CPK 8229, MB fraction 219, LDH 981. Chest X-ray and CT scan revealed bilateral patchy consolidations and ground-glass opacities. EMG was consistent with myositis. The patient was started on solumedrol 40 mg i.v., b.i.d., and then switched to prednisone 40 mg b.i.d. His symptoms and muscle strength improved remarkably. The patient was discharged with prednisone with an outpatient follow up.
一位 61 岁的白种人男性因进行性肌无力和体重减轻入住波兰比亚韦斯托克医科大学胸肺疾病和结核病科。入院前 18 个月,该患者被诊断为肺栓塞。当时,他开始接受依诺肝素 QD 治疗。既往病史无特殊。在此期间,患者出现发热、肌痛和进行性呼吸困难。入院时的体格检查显示上躯干和背部以及四肢的伸肌表面有皮疹。实验室检查结果包括肌酸磷酸激酶 8229、肌红蛋白片段 219、乳酸脱氢酶 981。胸部 X 线和 CT 扫描显示双侧斑片状实变和磨玻璃影。肌电图符合肌炎。患者开始静脉注射甲泼尼龙 40mg,bid,然后换用泼尼松 40mg,bid。他的症状和肌肉力量显著改善。患者出院时带泼尼松,并进行门诊随访。