Department of Chemistry, Virginia Polytechnic Institute and State University, Blacksburg, 24061-0212, USA.
Curr Med Chem. 2010;17(12):1191-219. doi: 10.2174/092986710790827834.
Madagascar, the world's fourth biggest island has an unique biodiversity. The interest on the phytochemical investigation of Malagasy plants and marine natural products started from the isolation of the potent anti-cancerous bisindole alkaloids: vinblastine and vincristine. In this paper, works published in the last two decades (1991-2009) on 270 new natural products isolated from Madagascar higher plants, liverworts and marine organisms are reviewed. Several results on the bioassays of the isolated new natural products have been reported.
马达加斯加是世界第四大岛屿，拥有独特的生物多样性。对马达加斯加植物和海洋天然产物的植物化学研究兴趣始于强效抗癌双吲哚生物碱：长春碱和长春新碱的分离。本文综述了过去二十年来（1991-2009 年）从马达加斯加高等植物、苔类植物和海洋生物中分离出的 270 种新型天然产物的研究成果。报道了一些关于分离出的新型天然产物的生物测定结果。
