University of Westminster, School of Life Sciences, 115, New Cavendish Street, London W1W 6UW, UK.
Reprod Biomed Online. 2010 Jan;20(1):98-102. doi: 10.1016/j.rbmo.2009.10.012. Epub 2009 Oct 30.
Cord blood stem cells have been in routine clinical practice for the past 20 years. The development of new therapeutic protocols in regenerative medicine require the use of stem cells and umbilical cord blood is an important and readily available source of cells for these applications. The latest concepts in routine transplantation of cord blood are reviewed followed by the critical role of cord blood stem cells in regenerative medicine research and novel approaches using cord blood as a source of whole blood for transfusion.
脐带血干细胞在过去的 20 年中已经在常规临床实践中得到应用。再生医学中治疗方案的发展需要使用干细胞,而脐带血是这些应用中细胞的重要且易于获得的来源。本文综述了脐带血常规移植的最新概念,以及脐带血干细胞在再生医学研究中的关键作用,以及使用脐带血作为输血来源的全血的新方法。