Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Pediatr Neurol. 2010 Mar;42(3):213-4. doi: 10.1016/j.pediatrneurol.2009.10.003.
Anti-N-methyl-D-aspartate receptor antibody has been associated with a severe stereotypic form of subacute encephalitis, often found in women with ovarian teratoma. Reported here is the diagnosis of anti-N-methyl-D-aspartate receptor encephalitis in a 5-year-old girl who presented with subacute encephalopathy and movement disorder without evidence of malignancy. Early diagnosis and treatment with immune globulin and steroids resulted in near-complete recovery.
抗 N-甲基-D-天冬氨酸受体抗体与一种严重的亚急性脑炎定型形式有关,这种脑炎通常发生在患有卵巢畸胎瘤的女性中。本文报道了一例 5 岁女孩的抗 N-甲基-D-天冬氨酸受体脑炎的诊断,该女孩表现为亚急性脑病和运动障碍,无恶性肿瘤证据。早期诊断和免疫球蛋白及类固醇治疗导致近乎完全恢复。