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饥饿大鼠重新喂食高蔗糖饮食后糖原积累、6-磷酸葡萄糖酸、果糖-2,6-二磷酸和脂肪生成的时间进程变化。

Time course changes in glycogen accretion, 6-phosphogluconate, fructose-2,6-bisphosphate, and lipogenesis upon refeeding a high sucrose diet to starved rats.

作者信息

Carmona A, Nishina P M, Avery E H, Freedland R A

机构信息

Department of Physiological Sciences, School of Veterinary Medicine, University of California-Davis 95616.

出版信息

Int J Biochem. 1991;23(4):455-60. doi: 10.1016/0020-711x(91)90173-k.

DOI:10.1016/0020-711x(91)90173-k
PMID:2015953
Abstract
  1. Starved rats refed 60% sucrose diets were used to determine in vivo lipogenesis and levels of hepatic metabolites. 2. Fatty acid synthesis increased 11-fold 4 hr after refeeding. 3. Glycogen rose from 3 to 100 mg/g liver after 8 hr. 4. Fructose-2,6-bisphosphate rose to 6 nmol/g at 1 hr and remained constant. 5. 6-Phosphogluconate increased from 10 to 45 nmol/g liver after 2 hr and remained constant.
摘要
  1. 用饥饿后再喂食60%蔗糖饮食的大鼠来测定体内脂肪生成及肝脏代谢物水平。2. 再喂食4小时后,脂肪酸合成增加了11倍。3. 8小时后,肝糖原从3毫克/克肝脏升至100毫克/克。4. 1小时时,果糖-2,6-二磷酸升至6纳摩尔/克并保持恒定。5. 2小时后,6-磷酸葡萄糖酸从10纳摩尔/克肝脏增至45纳摩尔/克并保持恒定。

相似文献

1
Time course changes in glycogen accretion, 6-phosphogluconate, fructose-2,6-bisphosphate, and lipogenesis upon refeeding a high sucrose diet to starved rats.饥饿大鼠重新喂食高蔗糖饮食后糖原积累、6-磷酸葡萄糖酸、果糖-2,6-二磷酸和脂肪生成的时间进程变化。
Int J Biochem. 1991;23(4):455-60. doi: 10.1016/0020-711x(91)90173-k.
2
Changes in fructose-2,6-bisphosphate levels after glucose loading of starved rats.饥饿大鼠葡萄糖负荷后果糖-2,6-二磷酸水平的变化
Biochem Biophys Res Commun. 1984 Jul 31;122(2):529-34. doi: 10.1016/s0006-291x(84)80065-0.
3
Regulation of hepatic fructose 2,6-bisphosphate concentrations and lipogenesis after re-feeding in euthyroid and hyperthyroid rats. A regulatory role for glycogenesis.正常甲状腺和甲状腺功能亢进大鼠再喂食后肝脏中果糖-2,6-二磷酸浓度及脂肪生成的调节。糖原生成的调节作用。
Biochem J. 1988 Jun 1;252(2):357-62. doi: 10.1042/bj2520357.
4
The regulation of lipogenesis in vivo in the lactating mammary gland of the rat during the starved-refed transition. Studies wtih acarbose, a glucosidase inhibitor.饥饿-再喂养过渡期大鼠泌乳乳腺体内脂肪生成的调节。使用阿卡波糖(一种葡萄糖苷酶抑制剂)的研究。
Biochem J. 1987 Feb 15;242(1):235-43. doi: 10.1042/bj2420235.
5
The disposition of carbohydrate between glycogenesis, lipogenesis and oxidation in liver during the starved-to-fed transition.饥饿至进食转变期间肝脏中碳水化合物在糖原生成、脂肪生成和氧化之间的分配情况。
Biochem J. 1988 Jun 1;252(2):325-30. doi: 10.1042/bj2520325.
6
Effects of diets on concentrations of 6-phosphogluconate and fructose 2,6-bisphosphate in rat livers and an assay of fructose 2,6-bisphosphate with an improved method.饮食对大鼠肝脏中6-磷酸葡萄糖酸和果糖2,6-二磷酸浓度的影响以及用改进方法测定果糖2,6-二磷酸
J Nutr. 1984 Aug;114(8):1462-9. doi: 10.1093/jn/114.8.1462.
7
Effect of diabetes, insulin, starvation, and refeeding on the level of rat hepatic fructose 2,6-bisphosphate.糖尿病、胰岛素、饥饿及再喂养对大鼠肝脏果糖-2,6-二磷酸水平的影响。
Diabetes. 1981 Dec;30(12):1062-4. doi: 10.2337/diab.30.12.1062.
8
Stoppage of glycogenesis and "over-shoot" of induction of lipogenesis and its related enzyme activities in the liver of fasted-refed rats.
J Nutr. 1976 Jan;106(1):136-41. doi: 10.1093/jn/106.1.136.
9
Active hepatic glycogen synthesis from gluconeogenic precursors despite high tissue levels of fructose 2,6-bisphosphate.尽管组织中果糖2,6-二磷酸水平很高,但仍能从糖异生前体物质中进行活跃的肝糖原合成。
J Biol Chem. 1986 Feb 25;261(6):2632-7.
10
Changes in rat hepatic fructose 2,6-bisphosphate and 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase activity during three days of consumption of a high protein diet or starvation.在食用高蛋白饮食或饥饿三天期间,大鼠肝脏中果糖-2,6-二磷酸及6-磷酸果糖-2-激酶/果糖-2,6-二磷酸酶活性的变化
Diabete Metab. 1987 Sep-Oct;13(5):543-8.

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Dynamics of the Glycogen β-Particle Number in Rat Hepatocytes during Glucose Refeeding.葡萄糖再喂养时大鼠肝细胞中糖原 β-粒子数的动态变化。
Int J Mol Sci. 2022 Aug 17;23(16):9263. doi: 10.3390/ijms23169263.
2
Effects of vanadate administration on the high sucrose diet-induced aberrations in normal rats.钒酸盐给药对高蔗糖饮食诱导的正常大鼠异常的影响。
Mol Cell Biochem. 1993 May 12;122(1):69-75. doi: 10.1007/BF00925739.