肝脏的发生和发育。
Organogenesis and development of the liver.
机构信息
Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA.
出版信息
Dev Cell. 2010 Feb 16;18(2):175-89. doi: 10.1016/j.devcel.2010.01.011.
PMID:20159590
Abstract
Embryonic development of the liver has been studied intensely, yielding insights that impact diverse areas of developmental and cell biology. Understanding the fundamental mechanisms that control hepatogenesis has also laid the basis for the rational differentiation of stem cells into cells that display many hepatic functions. Here, we review the basic molecular mechanisms that control the formation of the liver as an organ.
摘要
肝脏的胚胎发育一直是研究的热点，为发育和细胞生物学的多个领域提供了新的见解。了解控制肝发生的基本机制也为干细胞的合理分化为具有多种肝功能的细胞奠定了基础。本文综述了控制肝脏作为器官形成的基本分子机制。
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