Della Rocca Ylenia, Mazzone Antonella, Marconi Guya Diletta, Trubiani Oriana, Pizzicannella Jacopo, Diomede Francesca
Department of Innovative Technologies in Medicine & Dentistry, "G. d'Annunzio" University of Chieti-Pescara, Via dei Vestini, 31, 66100 Chieti, Italy.
Department of Engineering and Geology, "G. d'Annunzio" University of Chieti-Pescara, Viale Pindaro, 42, 65127 Pescara, Italy.
Int J Mol Sci. 2025 Aug 26;26(17):8255. doi: 10.3390/ijms26178255.
Regenerative medicine is the branch of medicine that aims to repair and regenerate damaged tissues and presents promising avenues for addressing a wide range of currently incurable diseases. Regenerative medicine is based on the use of cell therapy with stem cells that can differentiate into differentiated cells of specific tissues. There are various types of stem cells, which are different in potential and derivation. The aim of this review is to summarize the types of stem cells most studied and recently discovered, from adult stem cells to innovative induced pluripotent stem cells (iPSCs), for regenerative medicine purposes. The stem cells involved in the identification of new regenerative therapeutic approaches are analyzed here through a classification based on the tissues' embryonic derivation: stem cells from ectodermal derivation tissues, stem cells from mesodermal derivation tissues, stem cells from endodermal derivation tissues, and iPSCs.
再生医学是医学的一个分支，旨在修复和再生受损组织，并为解决目前多种无法治愈的疾病提供了有前景的途径。再生医学基于使用干细胞进行细胞治疗，这些干细胞可以分化为特定组织的分化细胞。干细胞有多种类型，其潜能和来源各不相同。本综述的目的是总结从成体干细胞到创新的诱导多能干细胞（iPSCs）等研究最多和最近发现的用于再生医学目的的干细胞类型。本文通过基于组织胚胎来源的分类来分析参与鉴定新的再生治疗方法的干细胞：外胚层来源组织的干细胞、中胚层来源组织的干细胞、内胚层来源组织的干细胞以及诱导多能干细胞。
