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因包裹 Fletcher-Williamson 阴道塞的聚砜帽而导致的剂量干扰。

Dose perturbation due to the polysulfone cap surrounding a Fletcher-Williamson colpostat.

机构信息

Department of Medical Physics, Mary Bird Perkins Cancer Center, Louisiana State University Baton Rouge, LA, USA.

出版信息

J Appl Clin Med Phys. 2010 Jan 28;11(1):3146. doi: 10.1120/jacmp.v11i1.3146.

Abstract

We conducted a metrological evaluation of the dosimetric impact due to the polysulfone cap used with the Fletcher-Williamson (FW) colpostat for 192Ir high-dose rate and pulsed-dose rate intracavitary brachytherapy using Monte Carlo simulations. Polysulfone caps with diameter of 30 mm, 25 mm, 20 mm, and 16 mm (mini-ovoid) were simulated and the absorbed dose rate in the surrounding water was calculated and compared to the dose rate for a bare 192Ir source in water. The dose perturbation depended on the cap diameter, distance away from the cap surface, and angular position around the cap. The largest dose rate reductions were found to be in the direction of the tumor bed where the cap is thickest. The range of perturbation over all depths and cap diameters was +2.8% (dose enhancement) to -6.8% (dose reduction). The FW colpostat cap's material composition should be modified to reduce this dosimetric effect or brachytherapy treatment planning dose algorithms should be improved to account for this perturbation.

摘要

我们使用蒙特卡罗模拟对使用 Fletcher-Williamson (FW) 柱状施源器的聚砜帽对 192Ir 高剂量率和脉冲剂量率腔内近距离治疗的剂量学影响进行了计量评估。模拟了直径为 30mm、25mm、20mm 和 16mm(迷你卵形)的聚砜帽,并计算了周围水中的吸收剂量率,并将其与水中裸露的 192Ir 源的剂量率进行了比较。剂量扰动取决于帽的直径、距帽表面的距离以及帽周围的角度位置。最大的剂量率降低发生在肿瘤床方向,因为那里的帽最厚。在所有深度和帽直径范围内,扰动范围为+2.8%(剂量增强)至-6.8%(剂量降低)。FW 柱状施源器帽的材料组成应进行修改,以减少这种剂量学效应,或者改进近距离治疗计划剂量算法,以考虑这种扰动。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c3e/5719781/7143cdf0c88a/ACM2-11-068-g001.jpg

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