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使用基于微纳加工音叉的传感器对硫衍生物进行选择性检测。

Selective Detection of Sulfur Derivatives Using Microfabricated Tuning Fork-Based Sensors.

作者信息

Rai Anant, Tsow Francis, Nassirpour Sanam, Bankers Jeffrey, Spinatsch Martina, He M Pete, Forzani Erica, Tao N J

机构信息

The Biodesign Institute and Department of Electrical Engineering, Arizona State University, Tempe, AZ 85287-5801.

出版信息

Sens Actuators B Chem. 2009 Jul 16;140(2):490-499. doi: 10.1016/j.snb.2009.04.053.

DOI:10.1016/j.snb.2009.04.053
PMID:20160943
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2765673/
Abstract

The paper describes an integtrated sensor system that can selectively and reversibly detect sulfur derivatives in the presence of interferent molecules. This is accomplished by integrating analyte-specific sensing materials with optimized filter materials. Microfabricated quartz tuning fork arrays are used to provide fast, accurate and low-cost transduction of the analyte binding events into electronic signals. The concept is demonstrated for detection of three sulfur derivatives - dimethyl disulfide, ethanethiol and methylsulfide.

摘要

本文描述了一种集成传感器系统,该系统能够在存在干扰分子的情况下选择性且可逆地检测硫衍生物。这是通过将分析物特异性传感材料与优化的过滤材料相结合来实现的。微加工石英音叉阵列用于将分析物结合事件快速、准确且低成本地转换为电信号。该概念通过检测三种硫衍生物——二甲基二硫、乙硫醇和甲硫醚得到了验证。

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使用RNA适体微阵列和酶促扩增表面等离子体共振成像检测蛋白质生物标志物。
Anal Chem. 2007 Feb 1;79(3):1082-8. doi: 10.1021/ac061849m.
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Biosens Bioelectron. 2007 Jan 15;22(6):1154-62. doi: 10.1016/j.bios.2006.07.040. Epub 2006 Sep 11.
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Anal Chem. 2006 Jun 1;78(11):3591-600. doi: 10.1021/ac052111s.
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A new surface plasmon resonance sensor for high-throughput screening applications.一种用于高通量筛选应用的新型表面等离子体共振传感器。
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