Atabaki Amir Hossein, Montazeri Abbas, Rafii-Tabar Hashem, Sasanpour Pezhman
Medical Physics and Biomedical Engineering, Shahid Beheshti University of Medical Sciences School of Medicine, Velenjak, Tehran, Tehran, 1985717443, Iran (the Islamic Republic of).
Materials Science and Engineering, KN Toosi University of Technology, Vanak Suare, Tehran, Tehran, 19697, Iran (the Islamic Republic of).
Biomed Phys Eng Express. 2021 Sep 14. doi: 10.1088/2057-1976/ac26a5.
In view of efficiency, simple operation, and affordable cost and disposability, quartz tuning fork systems form good candidates for mechanical-based biosensors in point of care applications. Based on the geometrical structure, the frequency response of the tuning fork- based sensors is dependent on the location of absorbed samples. In order to have the maximum efficiency and sensitivity, the optimized condition of sample loading on the fork structures should be considered. In this regard, here, we have determined the optimized sample location to be on the prongs of the quartz tuning fork by calculating the frequency response of the quartz tuning fork using the finite element method. From an application point of view, we have obtained an agreement between the calculational method and the experimental excitation technique of the structure. The results from our study show that by using an appropriate location for the sample, the quartz tuning fork could be exploited with high sensitivity.
鉴于效率高、操作简单、成本低廉且可一次性使用，石英音叉系统成为即时护理应用中基于机械的生物传感器的理想选择。基于几何结构，基于音叉的传感器的频率响应取决于吸收样品的位置。为了实现最高效率和灵敏度，应考虑音叉结构上样品加载的优化条件。在这方面，我们通过使用有限元方法计算石英音叉的频率响应，确定了优化的样品位置为石英音叉的叉臂上。从应用角度来看，我们在该结构的计算方法和实验激励技术之间取得了一致。我们的研究结果表明，通过为样品选择合适的位置，可以高灵敏度地利用石英音叉。
