• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Decarboxylative Cyclizations and Cycloadditions of Palladium-polarized Aza-ortho-Xylylenes.

作者信息

Wang Chao, Pahadi Nirmal, Tunge Jon A

机构信息

Department of Chemistry, The University of Kansas, 1251 Wescoe Hall Dr., Lawrence, KS 66045.

出版信息

Tetrahedron. 2009 Jun 27;65(26):5102-5109. doi: 10.1016/j.tet.2009.04.071.

DOI:10.1016/j.tet.2009.04.071
PMID:20161305
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2699301/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df15/2699301/ec2835f425c0/nihms113584f18.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df15/2699301/d90afd6ca851/nihms113584f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df15/2699301/01700cda293d/nihms113584f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df15/2699301/70fc5736d695/nihms113584f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df15/2699301/61b5ec2e50c8/nihms113584f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df15/2699301/0c8057964580/nihms113584f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df15/2699301/7fe990ce2f18/nihms113584f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df15/2699301/609a9884f580/nihms113584f7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df15/2699301/acdd1530b032/nihms113584f8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df15/2699301/da970d43bddc/nihms113584f9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df15/2699301/75ebea16c457/nihms113584f10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df15/2699301/388d8027e529/nihms113584f11.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df15/2699301/fb1500573338/nihms113584f12.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df15/2699301/409b87e7f94c/nihms113584f13.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df15/2699301/f975bf77f0c3/nihms113584f14.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df15/2699301/8bc94a5b8598/nihms113584f15.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df15/2699301/f76e5e5e9735/nihms113584f16.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df15/2699301/44305460e283/nihms113584f17.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df15/2699301/ec2835f425c0/nihms113584f18.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df15/2699301/d90afd6ca851/nihms113584f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df15/2699301/01700cda293d/nihms113584f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df15/2699301/70fc5736d695/nihms113584f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df15/2699301/61b5ec2e50c8/nihms113584f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df15/2699301/0c8057964580/nihms113584f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df15/2699301/7fe990ce2f18/nihms113584f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df15/2699301/609a9884f580/nihms113584f7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df15/2699301/acdd1530b032/nihms113584f8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df15/2699301/da970d43bddc/nihms113584f9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df15/2699301/75ebea16c457/nihms113584f10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df15/2699301/388d8027e529/nihms113584f11.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df15/2699301/fb1500573338/nihms113584f12.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df15/2699301/409b87e7f94c/nihms113584f13.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df15/2699301/f975bf77f0c3/nihms113584f14.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df15/2699301/8bc94a5b8598/nihms113584f15.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df15/2699301/f76e5e5e9735/nihms113584f16.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df15/2699301/44305460e283/nihms113584f17.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df15/2699301/ec2835f425c0/nihms113584f18.jpg

相似文献

1
Decarboxylative Cyclizations and Cycloadditions of Palladium-polarized Aza-ortho-Xylylenes.钯极化氮杂邻二甲苯的脱羧环化反应和环加成反应
Tetrahedron. 2009 Jun 27;65(26):5102-5109. doi: 10.1016/j.tet.2009.04.071.
2
Asymmetric cycloadditions of palladium-polarized aza-o-xylylenes.钯极化氮杂邻二甲苯的不对称环加成反应
J Am Chem Soc. 2008 Jul 2;130(26):8118-9. doi: 10.1021/ja801742h. Epub 2008 Jun 6.
3
Generation of aza-ortho-xylylenes via ring opening of 2-(2-acylaminophenyl)aziridines: application in the construction of the communesin ring system.通过2-(2-酰氨基苯基)氮丙啶的开环反应生成氮杂邻亚二甲苯：在共生素环系构建中的应用
Org Lett. 2006 Aug 31;8(18):3995-8. doi: 10.1021/ol061461d.
4
Palladium(0)-catalyzed intramolecular decarboxylative allylation of ortho nitrobenzoic esters.钯(0)催化邻硝基苯甲酸酯的分子内脱羧烯丙基化反应。
Org Lett. 2014 Aug 1;16(15):3934-7. doi: 10.1021/ol5017349. Epub 2014 Jul 23.
5
Diastereoselective Synthesis of Oxazoloisoindolinones via Cascade Pd-Catalyzed ortho-Acylation of N-Benzoyl α-Amino Acid Derivatives and Subsequent Double Intramolecular Cyclizations.通过 Pd 催化的 N-苯甲酰-α-氨基酸衍生物的邻位酰化和随后的双重分子内环化反应，立体选择性合成恶唑并异吲哚啉酮。
J Org Chem. 2019 Jan 4;84(1):161-172. doi: 10.1021/acs.joc.8b02509. Epub 2018 Dec 17.
6
Palladium-Catalyzed Decarboxylative ortho-Acylation of Benzamides with α-Oxocarboxylic Acids.钯催化的邻位酰化反应，使用α-氧代羧酸对苯甲酰胺进行脱羧。
J Org Chem. 2017 Dec 1;82(23):12715-12725. doi: 10.1021/acs.joc.7b02552. Epub 2017 Nov 21.
7
A highly efficient palladium-catalyzed decarboxylative ortho-acylation of azobenzenes with α-oxocarboxylic acids: direct access to acylated azo compounds.一种高效的钯催化的偶氮苯与α-氧代羧酸的脱羧邻位酰化反应：酰化偶氮化合物的直接合成。
Chemistry. 2013 Oct 18;19(43):14432-6. doi: 10.1002/chem.201301818. Epub 2013 Sep 23.
8
Pyrrolidines and Piperidines by Ligand-Enabled Aza-Heck Cyclizations and Cascades of N-(Pentafluorobenzoyloxy)carbamates.通过配体促进的氮杂-Heck环化反应以及N-（五氟苯甲酰氧基）氨基甲酸酯的串联反应合成吡咯烷和哌啶
Angew Chem Int Ed Engl. 2018 Apr 23;57(18):5124-5128. doi: 10.1002/anie.201801109. Epub 2018 Mar 22.
9
Palladium-Catalyzed Decarboxylative Ortho-Acylation of Tertiary Benzamides with Arylglyoxylic Acids.钯催化叔苯甲酰胺与芳基乙醛酸的脱羧邻酰化反应
ACS Omega. 2017 Jul 21;2(7):3806-3815. doi: 10.1021/acsomega.7b00717. eCollection 2017 Jul 31.
10
Merging Photoredox with Palladium Catalysis: Decarboxylative ortho-Acylation of Acetanilides with α-Oxocarboxylic Acids under Mild Reaction Conditions.光氧化还原与钯催化协同作用：温和反应条件下α-氧代羧酸对乙酰苯胺的脱羧邻位酰化反应。
Org Lett. 2015 Dec 18;17(24):6198-201. doi: 10.1021/acs.orglett.5b03192. Epub 2015 Dec 8.

引用本文的文献

1
Cooperative Dual Organocatalytic Asymmetric Decarboxylative [4 + 3] Annulations with Benzoxazinanones.苯并恶嗪酮参与的协同双有机催化不对称脱羧[4 + 3]环化反应
Precis Chem. 2023 Apr 4;1(4):241-247. doi: 10.1021/prechem.3c00019. eCollection 2023 Jun 26.
2
Catalyst-Controlled Annulations of Strained Cyclic Allenes with π-Allylpalladium Complexes.张力环丙酰胺与π-烯丙基钯配合物的催化剂控制环加成反应。
J Am Chem Soc. 2023 May 17;145(19):10491-10496. doi: 10.1021/jacs.3c03102. Epub 2023 May 4.
3
Synthesis of Tetra-Substituted Trifluoromethyl-3,1-Benzoxazines by Transition-Metal-Catalyzed Decarboxylative Cyclization of N-Benzoyl Benzoxazinones.通过N-苯甲酰基苯并恶嗪酮的过渡金属催化脱羧环化反应合成四取代三氟甲基-3,1-苯并恶嗪
ChemistryOpen. 2021 May;10(5):518-522. doi: 10.1002/open.202000360. Epub 2021 Feb 19.
4
Facile Access to Ring-Fused Aminals via Direct α-Amination of Secondary Amines with -Aminobenzaldehydes. Synthesis of Vasicine, Deoxyvasicine, Deoxyvasicinone, Mackinazolinone and Ruteacarpine.通过仲胺与α-氨基苯甲醛的直接α-胺化反应简便合成稠环缩醛胺。鸭嘴花碱、去氧鸭嘴花碱、去氧鸭嘴花酮碱、麦金鸡唑啉酮和吴茱萸次碱的合成。
Synthesis (Stuttg). 2013 Oct 6;45(13):1430-1748.
5
Metal-free α-amination of secondary amines: computational and experimental evidence for azaquinone methide and azomethine ylide intermediates.无金属的仲胺的α-胺化反应：氮宾甲烷和亚胺叶立德中间体的计算和实验证据。
J Org Chem. 2013 Apr 19;78(8):4132-44. doi: 10.1021/jo400483h. Epub 2013 Apr 2.
6
Migratory decarboxylative coupling of coumarins: synthetic and mechanistic aspects.香豆素的迁移脱羧偶联反应：合成及机理研究
Angew Chem Int Ed Engl. 2011 May 23;50(22):5157-61. doi: 10.1002/anie.201100765. Epub 2011 Apr 19.

本文引用的文献

1
Kinetics and Mechanisms of the Reactions of π-Allylpalladium Complexes with Nucleophiles.π-烯丙基钯配合物与亲核试剂反应的动力学及机理
Angew Chem Int Ed Engl. 1999 Feb 1;38(3):343-346. doi: 10.1002/(SICI)1521-3773(19990201)38:3<343::AID-ANIE343>3.0.CO;2-X.
2
Structure-based rationale for selectivity in the asymmetric allylic alkylation of cycloalkenyl esters employing the Trost 'Standard Ligand' (TSL): isolation, analysis and alkylation of the monomeric form of the cationic eta(3)-cyclohexenyl complex [(eta(3)-c-C6H9)Pd(TSL)]+.使用特罗斯特“标准配体”（TSL）对环烯基酯进行不对称烯丙基烷基化反应中选择性的基于结构的原理：阳离子η(3)-环己烯基络合物[(η(3)-c-C6H9)Pd(TSL)]⁺单体形式的分离、分析及烷基化反应
J Am Chem Soc. 2009 Jul 29;131(29):9945-57. doi: 10.1021/ja8099757.
3
Asymmetric cycloadditions of palladium-polarized aza-o-xylylenes.钯极化氮杂邻二甲苯的不对称环加成反应
J Am Chem Soc. 2008 Jul 2;130(26):8118-9. doi: 10.1021/ja801742h. Epub 2008 Jun 6.
4
Decarboxylative ring contractions and olefin insertions of vinyl oxazinanones.乙烯基恶唑烷酮的脱羧环收缩反应和烯烃插入反应
Org Lett. 2006 Jul 20;8(15):3211-4. doi: 10.1021/ol0610744.
5
Development of isomerization and cycloisomerization with use of a ruthenium hydride with N-heterocyclic carbene and its application to the synthesis of heterocycles.使用含氮杂环卡宾的氢化钌进行异构化和环异构化反应的开发及其在杂环合成中的应用。
J Org Chem. 2006 May 26;71(11):4255-61. doi: 10.1021/jo060308u.
6
Nitrogen heterocycles via palladium-catalyzed carbocyclization. Formal synthesis of (+)-alpha-allokainic acid.通过钯催化的碳环化反应合成氮杂环。（+）-α-别 kainic 酸的形式合成。
Org Lett. 2004 Jul 8;6(14):2481-4. doi: 10.1021/ol049087+.
7
Dynamic kinetic asymmetric cycloadditions of isocyanates to vinylaziridines.
J Am Chem Soc. 2003 Oct 1;125(39):11836-7. doi: 10.1021/ja037450m.
8
Electrophilicity parameters for benzylidenemalononitriles.
J Org Chem. 2003 Sep 5;68(18):6880-6. doi: 10.1021/jo0344182.
9
Hydrogen bond directed highly regioselective palladium-catalyzed allylic substitution.氢键导向的高度区域选择性钯催化烯丙基取代反应
J Am Chem Soc. 2003 Apr 30;125(17):5115-20. doi: 10.1021/ja028426w.
10
Palladium-catalyzed aminoallylation of activated olefins with allylic halides and phthalimide.钯催化的活性烯烃与烯丙基卤化物和邻苯二甲酰亚胺的氨基烯丙基化反应。
J Org Chem. 2002 Aug 23;67(17):5977-80. doi: 10.1021/jo025747h.